
Pre-made anti-IRE1a monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research.
Cat No.: GM-Tg-hg-T17656-Ab
Pre-made anti-IRE1a monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-IRE1a mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
The target: IRE1a, gene name: ERN1, also named as IRE1, IRE1P, IRE1a, hIRE1p. This gene encodes the transmembrane protein kinase inositol-requiring enzyme 1. The encoded protein contains two functional catalytic domains, a serine/threonine-protein kinase domain and an endoribonuclease domain. This protein functions as a sensor of unfolded proteins in the endoplasmic reticulum (ER) and triggers an intracellular signaling pathway termed the unfolded protein response (UPR). The UPR is an ER stress response that is conserved from yeast to mammals and activates genes involved in degrading misfolded proteins, regulating protein synthesis and activating molecular chaperones. This protein specifically mediates the splicing and activation of the stress response transcription factor X-box binding protein 1. [provided by RefSeq, Aug 2017].
Order information
* GeneMedi provides NON-PROFIT PRICE to support Academic research. Please click inquiry for product quotation. → Inquiry
Catalog No. | List Price (In USD) | Discount Price (In USD) | Qty (Quantity) | Sum (In USD) |
---|---|---|---|---|
GM-Tg-hg-T17656-Ab-1-1mg | 5150 | 3090 | ||
GM-Tg-hg-T17656-Ab-1-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-T17656-Ab-1-100mg | Inquiry | Inquiry | GM-Tg-hg-T17656-Ab-2-1mg | 5150 | 3090 |
GM-Tg-hg-T17656-Ab-2-10mg | Inquiry | Inquiry | ||
GM-Tg-hg-T17656-Ab-2-100mg | Inquiry | Inquiry | GM-Tg-hg-T17656-Ab-xmg | Inquiry | Inquiry |
Shipping Cost: | 760.00 | |||
Total: | ||||
Description
Catalog No. | GM-Tg-hg-T17656-Ab-1, GM-Tg-hg-T17656-Ab-2 |
Products Name | Anti-IRE1a/ERN1 monoclonal antibody |
Format | mab |
Target Name | IRE1a |
Gene ID | ERN1 |
Gene Name | ERN1 |
Gene Alias | IRE1, IRE1P, IRE1a, hIRE1p |
Protein Sub-location | Introcelluar Protein |
Category of antibody | |
Derivation (species) | Mouse |
Species Reactivity | Human(H) |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
Tag | Fc |
Products description | Pre-made anti-IRE1a monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
- GENEMEDI
- 6th Floor, Building No.2, Kangxin Road 3377, Shanghai, China
- Email: [email protected] [email protected]
- Telephone: +86-21-50478399 Fax: 86-21-50478399
- Privacy Policy
- TECHNICAL SUPPORT
- Product FAQs
- Technical manuals
- Publications
- Email: [email protected]
