Equine p-tau181 antibody and antigen (recombinant protein)

Diagnostic anti-Equine p-tau181 antibodies pairs and antigen for animal health (animal Equine/Horse Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Size: 1mg | 10mg | 100mg

Catalog No. Description US $ Price (per mg) First Order Discount First Order Discount Price
GMP-EQU-p-tau181-Ag01 Recombinant Equine p-tau181 protein 3090
GMP-EQU-p-tau181-Ab01 Anti-Equine p-tau181 mouse monoclonal antibody (mAb) 1953 20% 1562.4
GMP-EQU-p-tau181-Ab02 Anti-Equine p-tau181 mouse monoclonal antibody (mAb) 1953 20% 1562.4
GMP-EQU-p-tau181-Ab03 Anti-Equine p-tau181 mouse monoclonal antibody (mAb) 1953 20% 1562.4
GMP-EQU-p-tau181-Ab04 Anti-Equine p-tau181 mouse monoclonal antibody (mAb) 1953 20% 1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)



Product Description

Cat No. of Products GMP-EQU-p-tau181-Ag01
Product Name Recombinant Equine p-tau181 protein
Target/Biomarker Equine Phospho-tau181 (p-tau181)
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Equine Phospho-tau181 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in p-tau181 level test of animal Equine/Horse with Alzheimer Disease(AD).
Tag His
Products description Recombinant Equine p-tau181 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-EQU-p-tau181-Ab01, GMP-EQU-p-tau181-Ab02, GMP-EQU-p-tau181-Ab03, GMP-EQU-p-tau181-Ab04
Product Name Anti-Equine p-tau181 mouse monoclonal antibody (mAb)
Target/Biomarker Equine Phospho-tau181 (p-tau181)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Anti-Equine Phospho-tau181 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in p-tau181 level test of animal Equine/Horse with Alzheimer Disease(AD).
Tag mFc
Products description Anti-Equine p-tau181 mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Associated products


    • Recommend Pair Antibody and Antigen
    • Associated products
    Pair Antibody and Antigen Products detail Cat.No Product Name
    P-tau217 1. Antigen 1. GMP-h-p-tau217-Ag01 Phospho-tau217 (p-tau217) antigen
    2. Capture antibody 2. GMP-h-p-tau217-Ab01 Anti-human p-tau217 mouse monoclonal antibody(mAb)
    3. Detector antibody 3. GMP-h-Tau-Ab03 Recombinant human Tau Protein
    P-tau181 1. Antigen 1. GMP-h-p-tau181-Ag01 Phospho-tau181 (p-tau181) antigen
    2. Capture antibody 2. GMP-h-p-tau181-Ab01 Anti-human p-tau181 mouse monoclonal antibody(mAb)
    3. Detector antibody 3. GMP-h-Tau-Ab03 Recombinant human Tau Protein
    P-tau231 1. Antigen 1. GMP-h-p-tau231-Ag01 Phospho-tau231 (p-tau231) antigen
    2. Capture antibody 2. GMP-h-p-tau231-Ab01 Anti-human p-tau231 mouse monoclonal antibody(mAb)
    3. Detector antibody 3. GMP-h-Tau-Ab03 Recombinant human Tau Protein


    Catalog No. Products Name Biomarker Fc/Tag Products Information
    GMP-h-p-tau202/205-Ab Anti-human p-tau202 and 205 monoclonal antibody(mAb) Phospho-tau202 and 205 (p-tau202 and 205) hFc/mFc Details
    GMP-h-p-tau212/214-Ab Anti-human p-tau212 and 214 monoclonal antibody(mAb) Phospho-tau212 and 214 (p-tau212 and 214) hFc/mFc Details
    GMP-h-p-tau413-Ab Anti-human p-tau413 monoclonal antibody(mAb) Phospho-tau413 (p-tau413) hFc/mFc Details
    GMP-h-p-tau422-Ab Anti-human p-tau422 monoclonal antibody(mAb) Phospho-tau422 (p-tau422) hFc/mFc Details
    GMP-h-Tau-Ab Anti-human Tau monoclonal antibody(mAb) tau proteins (Tau) hFc/mFc Details

    Target/Biomarker information

    Equine p-tau181, the phosphorylated Tau Protein 181 variant specific to horses, is a beacon within the intricate landscape of equine neurobiology. At its core, it is a Tau protein that has undergone precise phosphorylation at residue 181. Under normal circumstances, Tau proteins serve as the guardians of microtubule stability within neuronal cells, ensuring proper intracellular transport and the structural integrity of axons. However, when neurodegenerative processes take center stage, the narrative evolves. Phosphorylation events can trigger the misfolding and aggregation of Tau proteins, and equine p-tau181 is no exception. It tends to aggregate and form neurofibrillary tangles within the neural tissues of afflicted horses. These neurofibrillary tangles, reminiscent of those observed in human neurodegenerative diseases such as Alzheimer's, are a pathological hallmark of various equine neurodegenerative conditions. The accumulation of p-tau181 in neurofibrillary tangles contributes to progressive neuronal dysfunction, ultimately manifesting as clinical signs in conditions like equine neuroaxonal dystrophy (eNAD) and specific encephalopathies.



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