Phospho-tau181 (p-tau181) antibody and antigen (Recombinant protein)

Diagnostic Phospho-tau181 (p-tau181) antibodies (anti-Phospho-tau181, anti-p-tau181) and antigens (recombinant Phospho-tau181 (p-tau181) protein) for Neurodegenerative diseases p-tau181 detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

Target products collectionGo to Neurodegenerative diseases diagnostics products collection >>


Product information

Catalog No. Description US $ Price (per mg)
GMP-h-p-tau181-Ag01 Phospho-tau181 (p-tau181) antigen $3090.00
GMP-h-p-tau181-Ag02 Phospho-tau181 (p-tau182) antigen (full length) $28000.00
GMP-h-p-tau181-Ab01 Anti-human p-tau181 mouse monoclonal antibody (mAb) $1953.00
GMP-h-p-tau181-Ab02 Anti-human p-tau181 mouse monoclonal antibody (mAb) $1953.00
GMP-h-p-tau181-Ab03 Anti-human p-tau181 human monoclonal antibody (mAb) $1953.00
GMP-h-p-tau181-Ab04 Anti-human p-tau181 human monoclonal antibody (mAb) $1953.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Pruducts GMP-h-p-tau181-Ag01
Product Name Phospho-tau181 (p-tau181) antigen
Target/Biomarker Phospho-tau181 (p-tau181)
Alias of Target/Biomarker DDPAC, FTDP-17L, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, tau-40, MAPT
Expression platform synthesized
Isotypes NA
Bioactivity validation Phospho-tau181 (p-tau181) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in p-tau181 level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation
Products description Recombinant Human Phospho-tau181 (p-tau181) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (HPLC)
Application positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts GMP-h-p-tau181-Ag02
Product Name Phospho-tau181 (p-tau181) antigen (full length)
Target/Biomarker Phospho-tau181 (p-tau181)
Alias of Target/Biomarker DDPAC, FTDP-17L, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, tau-40, MAPT
Expression platform mammalian
Isotypes Recombinant Antigen
Bioactivity validation Phospho-tau181 (p-tau181) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in p-tau181 level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation
Products description Recombinant Human Phospho-tau181 (p-tau181) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (HPLC)
Application positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts GMP-h-p-tau181-Ab01,GMP-h-p-tau181-Ab02
Product Name Anti-human p-tau181 mouse monoclonal antibody (mAb)
Target/Biomarker Phospho-tau181 (p-tau181)
Alias of Target/Biomarker DDPAC, FTDP-17L, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, tau-40, MAPT
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Human Phospho-tau181 (p-tau181) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Phospho-tau181 (p-tau181) antibodies in p-tau181 level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation.
Tag mFc
Products description Anti-human p-tau181 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Phospho-tau181 (p-tau181) antibodies.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. of Pruducts GMP-h-p-tau181-Ab03,GMP-h-p-tau181-Ab04
Product Name Anti-human p-tau181 human monoclonal antibody (mAb)
Target/Biomarker Phospho-tau181 (p-tau181)
Alias of Target/Biomarker DDPAC, FTDP-17L, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, tau-40, MAPT
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Human Phospho-tau181 (p-tau181) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Phospho-tau181 (p-tau181) antibodies in p-tau181 level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation.
Tag hFc
Products description Anti-human p-tau181 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study



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    • Figure A: GeneMedi's GMP-h-p-tau181-Ab01 (Anti-human p-tau181 antibody) is validated to detect the GMP-h-p-tau181-Ag01 (p-tau181 antigen) in ELISA, EC50 = 25.26ng/ml.

    • Figure B: GeneMedi's GMP-h-p-tau217-Ab01 (Anti-human p-tau217 antibody) is validated to detect the GMP-h-p-tau217-Ag01 (p-tau217 antigen) in ELISA, EC50 = 25.85ng/ml.

    • Figure C: GeneMedi's GMP-h-p-tau231-Ab01 (Anti-human p-tau231 antibody) is validated to detect the GMP-h-p-tau231-Ag01 (p-tau231 antigen) in ELISA. EC50 = 64.34ng/ml.


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Alzheimer Disease(AD)  Recent publications and meeting presentations bolster the evidence that upticks in p-tau181, p-tau217, and p-tau231 occur soon after Aβ begins to accumulate in the brain. That’s years before neurofibrillary tangles can be detected by PET, and decades before symptoms. Researchers predict these markers, which also distinguish AD from other forms of dementia, will lead to more robust tests than those based on Aβ, because of their larger dynamic range—phosphorylated fragments of tau climb by as much as 10-fold in the blood as AD progresses, whereas the Aβ42/40 ratio falls by about 15 percent at most.



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    GDU

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