Phospho-tau202 and 205 (p-tau202 and 205) antibody and antigen (Recombinant protein)

Diagnostic Phospho-tau202 and 205 (p-tau202 and 205) antibodies (anti-Phospho-tau202 and 205, anti-p-tau202 and 205) and antigens (recombinant Phospho-tau202 and 205 (p-tau202 and 205) protein) for Neurodegenerative diseases p-tau202 and 205 detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

Target products collectionGo to Neurodegenerative diseases diagnostics products collection >>


Product information

Catalog No. Description US $ Price (per mg)
GMP-h-p-tau202/205-Ag01 Phospho-tau202 and 205 (p-tau202 and 205) antigen $3090.00
GMP-h-p-tau202/205-Ab01 Anti-human p-tau202 and 205 mouse monoclonal antibody (mAb) $1953.00
GMP-h-p-tau202/205-Ab02 Anti-human p-tau202 and 205 mouse monoclonal antibody (mAb) $1953.00
GMP-h-p-tau202/205-Ab03 Anti-human p-tau202 and 205 human monoclonal antibody (mAb) $1953.00
GMP-h-p-tau202/205-Ab04 Anti-human p-tau202 and 205 human monoclonal antibody (mAb) $1953.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Pruducts GMP-h-p-tau202/205-Ag01
Product Name Phospho-tau202 and 205 (p-tau202 and 205) antigen
Target/Biomarker Phospho-tau202 and 205 (p-tau202 and 205)
Alias of Target/Biomarker DDPAC, FTDP-17L, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, tau-40, MAPT
Expression platform synthesized
Isotypes NA
Bioactivity validation Phospho-tau202 and 205 (p-tau202 and 205) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in p-tau202 and 205 level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation
Products description Recombinant Human Phospho-tau202 and 205 (p-tau202 and 205) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (HPLC)
Application positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts GMP-h-p-tau202/205-Ab01,GMP-h-p-tau202/205-Ab02
Product Name Anti-human p-tau202 and 205 mouse monoclonal antibody (mAb)
Target/Biomarker Phospho-tau202 and 205 (p-tau202 and 205)
Alias of Target/Biomarker DDPAC, FTDP-17L, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, tau-40, MAPT
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Human Phospho-tau202 and 205 (p-tau202 and 205) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Phospho-tau202 and 205 (p-tau202 and 205) antibodies in p-tau202 and 205 level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation.
Tag mFc
Products description Anti-human p-tau202 and 205 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Phospho-tau202 and 205 (p-tau202 and 205) antibodies.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. of Pruducts GMP-h-p-tau202/205-Ab03,GMP-h-p-tau202/205-Ab04
Product Name Anti-human p-tau202 and 205 human monoclonal antibody (mAb)
Target/Biomarker Phospho-tau202 and 205 (p-tau202 and 205)
Alias of Target/Biomarker DDPAC, FTDP-17L, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU, tau-40, MAPT
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Human Phospho-tau202 and 205 (p-tau202 and 205) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Phospho-tau202 and 205 (p-tau202 and 205) antibodies in p-tau202 and 205 level test of Neurodegenerative diseases (Alzheimer Disease(AD)) and related syndrome evaluation.
Tag hFc
Products description Anti-human p-tau202 and 205 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Associated products


    • Recommend Pair Antibody and Antigen
    • Associated products
    Pair Antibody and Antigen Products detail Cat.No Product Name
    P-tau217 1. Antigen 1. GMP-h-p-tau217-Ag01 Phospho-tau217 (p-tau217) antigen
    2. Capture antibody 2. GMP-h-p-tau217-Ab01 Anti-human p-tau217 mouse monoclonal antibody(mAb)
    3. Detector antibody 3. GMP-h-Tau-Ab03 Recombinant human Tau Protein
    P-tau181 1. Antigen1. GMP-h-p-tau181-Ag01 Phospho-tau181 (p-tau181) antigen
    2. Capture antibody 2. GMP-h-p-tau181-Ab01 Anti-human p-tau181 mouse monoclonal antibody(mAb)
    3. Detector antibody 3. GMP-h-Tau-Ab03 Recombinant human Tau Protein
    P-tau231 1. Antigen1. GMP-h-p-tau231-Ag01 Phospho-tau231 (p-tau231) antigen
    2. Capture antibody 2. GMP-h-p-tau231-Ab01 Anti-human p-tau231 mouse monoclonal antibody(mAb)
    3. Detector antibody 3. GMP-h-Tau-Ab03 Recombinant human Tau Protein


    Catalog No. Products Name Biomarker Fc/Tag Products Information
    GMP-h-p-tau202/205-Ab Anti-human p-tau202 and 205 monoclonal antibody(mAb) Phospho-tau202 and 205 (p-tau202 and 205) hFc/mFc Details
    GMP-h-p-tau212/214-Ab Anti-human p-tau212 and 214 monoclonal antibody(mAb) Phospho-tau212 and 214 (p-tau212 and 214) hFc/mFc Details
    GMP-h-p-tau413-Ab Anti-human p-tau413 monoclonal antibody(mAb) Phospho-tau413 (p-tau413) hFc/mFc Details
    GMP-h-p-tau422-Ab Anti-human p-tau422 monoclonal antibody(mAb) Phospho-tau422 (p-tau422) hFc/mFc Details
    GMP-h-Tau-Ab Anti-human Tau monoclonal antibody(mAb) tau proteins (Tau) hFc/mFc Details

    Target/Biomarker information

    Alzheimer's disease (AD) is a neurodegenerative disorder characterized by abnormal accumulation of tau protein, which plays a crucial role in maintaining the structure of nerve cells. Recent findings suggest that the phosphorylated tau fragments, such as p-tau181, p-tau217, p-tau231, and p-tau202 and 205, start to increase in the brain soon after amyloid-beta (Aβ) accumulation, years before neurofibrillary tangles are detected, and decades before symptoms appear. These markers have a larger dynamic range compared to Aβ and can distinguish AD from other forms of dementia more accurately. For instance, phosphorylated tau fragments climb up to 10-fold in blood levels as AD progresses, while the Aβ42/40 ratio falls by only about 15 percent. Monoclonal antibodies such as AT8, AT100, AT180, and AT270 have been developed to target various forms of tau protein. AT8 specifically recognizes tau phosphorylated at serine 202 and threonine 205 sites and has been used to identify abnormal tau protein accumulation in Alzheimer's disease. AT100 targets phosphorylated tau at threonine 212 and serine 214 sites, and has been shown to detect early stage neurofibrillary pathology in AD. AT180 binds to phosphorylated tau at threonine 231 site and is useful in understanding the relationship between tau protein phosphorylation and neurodegeneration. AT270 targets phosphorylated tau at threonine 181 site and has been reported to detect elevated tau protein levels in cerebrospinal fluid of AD patients. These monoclonal antibodies serve as valuable research tools for studying the pathological mechanisms underlying neurodegenerative diseases such as Alzheimer's disease.



    About GDU


    GDU

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    Comments


    Mary Anderson 2023-10-16 17:57:31
    The antigen is highly stable and provides excellent data quality, ideal for Lateral Flow Immunoassay (LFIA). It ensures dependable diagnostic outcomes.

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