Equine p-tau212 and 214 antibody and antigen (recombinant protein)
Diagnostic anti-Equine p-tau212 and 214 antibodies pairs and antigen for animal health (animal Equine/Horse Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-EQU-p-tau212-214-Ag01 | Recombinant Equine p-tau212 and 214 protein | 3090 |
GMP-EQU-p-tau212-214-Ab01 | Anti-Equine p-tau212 and 214 mouse monoclonal antibody (mAb) | 3090 |
GMP-EQU-p-tau212-214-Ab02 | Anti-Equine p-tau212 and 214 mouse monoclonal antibody (mAb) | 3090 |
GMP-EQU-p-tau212-214-Ab03 | Anti-Equine p-tau212 and 214 human monoclonal antibody (mAb) | 3090 |
GMP-EQU-p-tau212-214-Ab04 | Anti-Equine p-tau212 and 214 human monoclonal antibody (mAb) | 3090 |
Size: 1mg | 10mg | 100mg
Product Description
Cat No. of Products | GMP-EQU-p-tau212-214-Ag01 |
Product Name | Recombinant Equine p-tau212 and 214 protein |
Target/Biomarker | Equine Phospho-Tau212 And 214 (p-tau212 and 214) |
Alias of Target/Biomarker | Equine Phospho-Tau212 And 214 (p-tau212 and 214) |
Expression platform | E.coli |
Isotypes | Recombinant Antigen |
Bioactivity validation | Anti-Equine Phospho-Tau212 And 214 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in p-tau212 and 214 level test of animal Equine/Horse with Alzheimer Disease(AD). |
Tag | His |
Products description | Recombinant Equine p-tau212 and 214 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays |
Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. of Products | GMP-EQU-p-tau212-214-Ab01, GMP-EQU-p-tau212-214-Ab02 |
Product Name | Anti-Equine p-tau212 and 214 mouse monoclonal antibody (mAb) |
Target/Biomarker | Equine Phospho-Tau212 And 214 (p-tau212 and 214) |
Alias of Target/Biomarker | Equine Phospho-Tau212 And 214 (p-tau212 and 214) |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Recombinant Equine Phospho-Tau212 And 214 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-p-tau212 and 214 antibodies in p-tau212 and 214 level test of animal Equine/Horse with Alzheimer Disease(AD). |
Tag | mFc |
Products description | Anti-Equine p-tau212 and 214 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-p-tau212 and 214 antibodies. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays |
Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. of Products | GMP-EQU-p-tau212-214-Ab03, GMP-EQU-p-tau212-214-Ab04 |
Product Name | Anti-Equine p-tau212 and 214 human monoclonal antibody (mAb) |
Target/Biomarker | Equine Phospho-Tau212 And 214 (p-tau212 and 214) |
Alias of Target/Biomarker | Equine Phospho-Tau212 And 214 (p-tau212 and 214) |
Expression platform | CHO |
Isotypes | Human IgG1 |
Bioactivity validation | Recombinant Equine Phospho-Tau212 And 214 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-p-tau212 and 214 antibodies in p-tau212 and 214 level test of animal Equine/Horse with Alzheimer Disease(AD). |
Tag | hFc |
Products description | Anti-Equine p-tau212 and 214 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-p-tau212 and 214 antibodies. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays |
Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Associated products
- Recommend Pair Antibody and Antigen
- Associated products
Pair Antibody and Antigen | Products detail | Cat.No | Product Name |
P-tau217 | 1. Antigen | 1. GMP-h-p-tau217-Ag01 | Phospho-tau217 (p-tau217) antigen |
2. Capture antibody | 2. GMP-h-p-tau217-Ab01 | Anti-human p-tau217 mouse monoclonal antibody(mAb) | |
3. Detector antibody | 3. GMP-h-Tau-Ab03 | Recombinant human Tau Protein | |
P-tau181 | 1. Antigen | 1. GMP-h-p-tau181-Ag01 | Phospho-tau181 (p-tau181) antigen |
2. Capture antibody | 2. GMP-h-p-tau181-Ab01 | Anti-human p-tau181 mouse monoclonal antibody(mAb) | |
3. Detector antibody | 3. GMP-h-Tau-Ab03 | Recombinant human Tau Protein | |
P-tau231 | 1. Antigen | 1. GMP-h-p-tau231-Ag01 | Phospho-tau231 (p-tau231) antigen |
2. Capture antibody | 2. GMP-h-p-tau231-Ab01 | Anti-human p-tau231 mouse monoclonal antibody(mAb) | |
3. Detector antibody | 3. GMP-h-Tau-Ab03 | Recombinant human Tau Protein |
Catalog No. | Products Name | Biomarker | Fc/Tag | Products Information |
GMP-h-p-tau202/205-Ab | Anti-human p-tau202 and 205 monoclonal antibody(mAb) | Phospho-tau202 and 205 (p-tau202 and 205) | hFc/mFc | Details |
GMP-h-p-tau212/214-Ab | Anti-human p-tau212 and 214 monoclonal antibody(mAb) | Phospho-tau212 and 214 (p-tau212 and 214) | hFc/mFc | Details |
GMP-h-p-tau413-Ab | Anti-human p-tau413 monoclonal antibody(mAb) | Phospho-tau413 (p-tau413) | hFc/mFc | Details |
GMP-h-p-tau422-Ab | Anti-human p-tau422 monoclonal antibody(mAb) | Phospho-tau422 (p-tau422) | hFc/mFc | Details |
GMP-h-Tau-Ab | Anti-human Tau monoclonal antibody(mAb) | tau proteins (Tau) | hFc/mFc | Details |
Target/Biomarker information
Equine p-tau212 and p-tau214 represent a subset of tau proteins specific to the equine neurological landscape. These phosphorylated tau variants are intricately involved in maintaining the structural stability of microtubules within neurons. Under normal circumstances, tau proteins bind to microtubules and aid in their assembly, ensuring proper neuronal function, axonal transport, and synaptic communication. However, the equilibrium in tau phosphorylation is delicate, and when disrupted, it can have far-reaching consequences. In equine neurodegenerative disorders, such as certain tauopathies, aberrant phosphorylation of tau proteins occurs. This post-translational modification leads to tau proteins adopting abnormal conformations, which renders them prone to aggregation. The aggregation of tau proteins culminates in the formation of neurofibrillary tangles, a pathological hallmark reminiscent of similar neurodegenerative diseases in humans, like Alzheimer's disease. Equine p-tau212 and p-tau214, phosphorylated at specific sites within the tau protein sequence, are indicative of this pathological cascade. They serve as early indicators of tauopathy-related neurodegenerative processes in horses. The presence of elevated levels of these biomarkers suggests ongoing tau phosphorylation and the potential emergence of cognitive and neurological deficits in affected equines.
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