Equine p-tau231 antibody and antigen (recombinant protein)

Diagnostic anti-Equine p-tau231 antibodies pairs and antigen for animal health (animal Equine/Horse Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-p-tau231-Ag01Equine p-tau231$3090.00
GMP-EQU-p-tau231-Ab01Anti-Equine p-tau231 mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-p-tau231-Ab02Anti-Equine p-tau231 mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-p-tau231-Ab03Anti-Equine p-tau231 human monoclonal antibody (mAb)$3090.00
GMP-EQU-p-tau231-Ab04Anti-Equine p-tau231 human monoclonal antibody (mAb)$3090.00

Size： 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-p-tau231-Ag01
Product NameEquine p-tau231
Target/BiomarkerEquine p-tau231
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine p-tau231 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in p-tau231 level test of animal Equine/Horse with Alzheimer Disease(AD).
TagHis
Reconized/Reactive SpecicsEquine p-tau231
Product descriptionRecombinant Equine p-tau231 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-p-tau231-Ab01,GMP-EQU-p-tau231-Ab02
Target/BiomarkerEquine p-tau231
Product NameAnti-Equine p-tau231 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine p-tau231 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine p-tau231 antibodies in Equine p-tau231 level test of animal Equine/Horse with Alzheimer Disease(AD).
Product descriptionAnti-Equine p-tau231 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine p-tau231 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-p-tau231-Ab03,GMP-EQU-p-tau231-Ab04
Target/BiomarkerEquine p-tau231
Product NameAnti-Equine p-tau231 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine p-tau231 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine p-tau231 antibodies in Equine p-tau231 level test of animal Equine/Horse with Alzheimer Disease(AD).
Product descriptionAnti-Equine p-tau231 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Equine p-tau231, the phosphorylated Tau Protein 231 variant specific to horses, stands as a sentinel within the intricate landscape of equine neurobiology. At its core, it is a Tau protein that has undergone precise phosphorylation at residue 231. Tau proteins, under normal circumstances, play a vital role in stabilizing microtubules within neuronal cells, ensuring proper intracellular transport and the structural integrity of axons.

    However, in the context of neurodegenerative diseases, the narrative takes a different turn. Phosphorylation events can lead to the misfolding and aggregation of Tau proteins, and equine p-tau231 is no exception. It tends to aggregate and form neurofibrillary tangles within the neural tissues of afflicted horses.

    These neurofibrillary tangles, reminiscent of those observed in human neurodegenerative diseases like Alzheimer's, serve as a pathological hallmark of various equine neurodegenerative conditions. The accumulation of p-tau231 in neurofibrillary tangles contributes to progressive neuronal dysfunction, ultimately manifesting as clinical signs in conditions such as equine neuroaxonal dystrophy (eNAD) and specific encephalopathies.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.