Chlamydia psittaci antibody and antigen (recombinant protein)

Diagnostic anti-Chlamydia psittaci antibodies pairs and antigen for animal health (animal Parrot infectious disease Psittacosi) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P184-Ag01 Recombinant Chlamydia psittaci protein $3090.00
GMP-VT-P184-Ab01 Anti-Chlamydia psittaci mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P184-Ab02 Anti-Chlamydia psittaci mouse monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P184-Ag01
Product Name Recombinant Chlamydia psittaci protein
Pathogen Chlamydia psittaci
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Chlamydia psittaci antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Chlamydia psittaci level test of animal Parrot infectious disease with Psittacosi.
Tag His
Product description Recombinant Chlamydia psittaci proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P184-Ab01,GMP-VT-P184-Ab02
Pathogen Chlamydia psittaci
Product Name Anti-Chlamydia psittaci mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Chlamydia psittaci antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Chlamydia psittaci antibodies in Chlamydia psittaci level test of animal Parrot infectious disease with Psittacosi.
Product description Anti-Chlamydia psittaci mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Chlamydia psittaci antibodies./td>
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Pathogen


    Chlamydia psittaci is a Gram-negative bacterium that belongs to the phylum Chlamydiae. The bacteria's name is derived from the Greek word "khlamydos," meaning cloak or mantle, and its unique characteristic of forming a cytoplasmic inclusion called the chlamydial body. Chlamydia psittaci is an obligate intracellular pathogen, which means it is only able to replicate inside host cells. It has a complex life cycle that involves two distinct forms: the elementary body (EB) and the reticulate body (RB).

    The outer membrane of Chlamydia psittaci is composed of lipopolysaccharides and proteins. The bacterial cell wall is thin and lacks peptidoglycan, which is typically found in other Gram-negative bacteria. This unique feature contributes to its ability to replicate intracellularly. The inner membrane contains phospholipids and several proteins that are involved in transport and metabolism.

    The most significant protein of Chlamydia psittaci is the major outer membrane protein (MOMP), which is encoded by the ompA gene. MOMP is highly conserved among different Chlamydia species and is a critical target for diagnosis and vaccine development. Studies have shown that MOMP plays a crucial role in both host immune response and pathogenicity of Chlamydia psittaci.

    Chlamydia psittaci primarily infects avian species, particularly psittacine birds such as parrots, but it can also infect other animals such as poultry, pigeons, and mammals including humans. Infection with Chlamydia psittaci can result in psittacosis, a respiratory disease that can range in severity from mild flu-like symptoms to severe pneumonia. In humans, the disease is typically acquired through exposure to infected birds or their excreta. The bacteria can be transmitted through inhalation of contaminated dust or by direct contact with infected birds.

    To diagnose Chlamydia psittaci infection, various methods are available, including culture, serology, polymerase chain reaction (PCR), and nucleic acid amplification tests (NAATs). Serological tests detect specific antibodies produced by the host in response to infection with Chlamydia psittaci. PCR-based assays have been developed to detect the bacteria's DNA in clinical specimens, providing an accurate and sensitive method for diagnosis. The ompA gene is a common target for PCR-based assays, as it is highly conserved among different Chlamydia species.

    Chlamydia psittaci poses a significant threat to public health as a zoonotic agent. Outbreaks of psittacosis have occurred in bird owners, bird handlers, and workers in bird-processing facilities. Prompt diagnosis and treatment of the disease are crucial to prevent morbidity and mortality associated with this highly infectious respiratory disease.

    In conclusion, Chlamydia psittaci is a unique obligate intracellular Gram-negative bacterium that has evolved a sophisticated life cycle to survive and replicate within host cells. The development of effective diagnostic methods is essential to facilitate early detection and treatment of Chlamydia psittaci infection. Additionally, understanding the biology of this pathogen is critical for the development of effective vaccines and therapeutic agents to combat this significant public health threat.



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