Avibacterium paragallinarum antibody and antigen (recombinant protein)

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Diagnostic anti-Avibacterium paragallinarum antibodies pairs and antigen for animal health (animal Chicken infectious disease Infectious coryza) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P200-Ag01	Recombinant Avibacterium paragallinarum protein	$3090.00
GMP-VT-P200-Ab01	Anti-Avibacterium paragallinarum mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P200-Ab02	Anti-Avibacterium paragallinarum mouse monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P200-Ag01
Product Name	Recombinant Avibacterium paragallinarum protein
Pathogen	Avibacterium paragallinarum
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Avibacterium paragallinarum antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Avibacterium paragallinarum level test of animal Chicken infectious disease with Infectious coryza.
Tag	His
Product description	Recombinant Avibacterium paragallinarum proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P200-Ab01,GMP-VT-P200-Ab02
Pathogen	Avibacterium paragallinarum
Product Name	Anti-Avibacterium paragallinarum mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Avibacterium paragallinarum antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avibacterium paragallinarum antibodies in Avibacterium paragallinarum level test of animal Chicken infectious disease with Infectious coryza.
Product description	Anti-Avibacterium paragallinarum mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avibacterium paragallinarum antibodies./td>
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen

Avibacterium paragallinarum is a gram-negative bacterium that belongs to the Pasteurellaceae family. As a facultatively anaerobic organism, it can tolerate both aerobic and anaerobic environments. The pathogen possesses a cell wall composed of peptidoglycan and lipopolysaccharides, which helps protect it from host immune responses. Its genome contains various virulence genes, including the KMT1 gene and the hemoglobin/haptoglobin-binding protein.

Avibacterium paragallinarum mainly infects chickens and other avian species, causing respiratory disease, sinusitis, and infectious coryza. In addition to these symptoms, infected birds may also exhibit conjunctivitis, nasal discharge, facial swelling, and a decrease in egg production. The bacterium can be transmitted through direct contact with infected birds or indirect contact via contaminated equipment or surfaces.

To diagnose Avibacterium paragallinarum infection, several methods are available. Bacterial culture involves isolating the bacteria from a swab or tissue sample collected from an infected bird. Polymerase chain reaction (PCR) is a molecular method that can detect specific DNA sequences of Avibacterium paragallinarum. Enzyme-linked immunosorbent assay (ELISA) is an immunological method that detects the presence of antibodies against the pathogen. Hemagglutination tests involve agglutination of red blood cells in response to the presence of the pathogen.

In addition to these standard diagnostic methods, researchers are also exploring novel approaches for detecting Avibacterium paragallinarum. For example, loop-mediated isothermal amplification (LAMP) is a technique that amplifies specific DNA sequences of the pathogen at a constant temperature. This method is faster and more efficient than traditional PCR, making it an attractive option for diagnostic labs.

Treatment of Avibacterium paragallinarum infection typically involves antibiotics such as oxytetracycline or sulfonamides. However, the emergence of antibiotic-resistant strains of the pathogen has become a significant concern in recent years. In response, researchers are exploring alternative approaches to managing the disease, including vaccination and probiotics.

In conclusion, Avibacterium paragallinarum is a gram-negative bacterium that causes respiratory disease, sinusitis, and infectious coryza in chickens and other avian species. Several diagnostic methods are available, including bacterial culture, PCR, ELISA, and hemagglutination tests. Treatment typically involves antibiotics, but alternative approaches such as vaccination and probiotics are also being investigated.

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