Products & Information Collection of New variant SARS-COV-2 (2019nCOV) -The delta variant B.1.617.2 lineage

The world is in midst of the COVID-19 pandemic. Previously known as B.1.617.2, the variant was first discovered in India in February, where it contributed to a horrific wave of infections which started in the spring: The Economist estimates that there have been more than 1m covid deaths in India this year. The delta variant has spread rapidly across borders, too. According to GISAID, the mutation has been identified in at least 70 countries. The delta variant is the most dangerous SARS-CoV-2 mutation yet.¹

Mutations of Spike protein in SARS-COV-2 (2019nCOV) delta variant B.1.617.2 lineage

Two of the spike mutations are at key residues in the RBD (L452R and T478K), two are in the N-terminal domain (T19R and FR157-158Δ).².
Figure. Amino acid changes in the spike region of the 190 S501Y.V2 genomes²,³

GeneMedi pseudotype virus (pseudovirus) of SARS-COV-2 (2019nCOV) delta variant B.1.617.2 lineage

SARS-COV-2 (2019nCOV) -delta variant B.1.617.2 lineage of Spike protein & ACE2 competition binding assay for efficacy evaluation of COVID-19 vaccines and therapeutic antibodies

GeneMedi codon-optimized spike mammalian expression vector for SARS-COV-2 (2019nCOV) -delta variant B.1.617.2 lineage

Reference

1.The delta variant is the most dangerous SARS-CoV-2 mutation yet. https://www.economist.com/graphic-detail/2021/06/16/-delta-variant-is-the-most-dangerous-sars-cov-2-mutation-yet.

2.B.1.617.2 lineage Report. https://outbreak.info/situation-reports?pango=B.1.617.2.

3.Spike Variants. https://covdb.stanford.edu/page/mutation-viewer/#sec_delta.