Human CALR ORF/cDNA clone-Adenovirus plasmid (BC002500)

Pre-made Human CALR/ adenoviral expression plasmid for CALR adenovirus packaging, CALR adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

Target products collectionGo to CALR/ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMAP000540 / Adenovirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMAP000540
Gene Name CALR
Accession Number BC002500
Gene ID 811
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 1871 bp
Gene Alias
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T79821-Ab Anti-CALR/ CRT/ HEL-S-99n functional antibody
    Target Antigen GM-Tg-g-T79821-Ag CALR protein
    ORF Viral Vector pGMAD000312 Rat Calr Adenovirus plasmid
    ORF Viral Vector pGMPC000518 Human CALR Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMPC000799 Human CALR Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMLP000141 Human CALR Lentivirus plasmid
    ORF Viral Vector pGMAP000540 / Adenovirus plasmid
    ORF Viral Vector vGMAD000312 Rat Calr Adenovirus particle
    ORF Viral Vector vGMLP000141 Human CALR Lentivirus particle
    ORF Viral Vector vGMAP000540 / Adenovirus particle


    Target information

    Target ID GM-T79821
    Target Name CALR
    Gene ID 811, 12317, 716910, 64202, 101087384, 476694, 281036, 100064107
    Gene Symbol and Synonyms CALR,CALR1,Calregulin,cC1qR,CRP55,CRT,ERp60,HACBP,HEL-S-99n,RO,SSA
    Uniprot Accession P27797
    Uniprot Entry Name CALR_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Immuno-oncology Target
    Disease Prostate Cancer, Malignant neoplasm of bladder
    Gene Ensembl ENSG00000179218
    Target Classification Checkpoint-Immuno Oncology

    Calreticulin is a highly conserved chaperone protein which resides primarily in the endoplasmic reticulum, and is involved in a variety of cellular processes, among them, cell adhesion. Additionally, it functions in protein folding quality control and calcium homeostasis. Calreticulin is also found in the nucleus, suggesting that it may have a role in transcription regulation. Systemic lupus erythematosus is associated with increased autoantibody titers against calreticulin. Recurrent mutations in calreticulin have been linked to various neoplasms, including the myeloproliferative type.[provided by RefSeq, May 2020]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.