Human NFKB1/KBF1/ EBP-1 ORF/cDNA clone-Adenovirus plasmid (BC051765)

Pre-made Human NFKB1/KBF1/ EBP-1 adenoviral expression plasmid for NFKB1 adenovirus packaging, NFKB1 adenovirus.

Our GM-Adenovirus vector is optimized with the GMVC-modified Adeasy adenovirus packaging system. Find more about the GMVC-modified adenovirus packaging system.

Target products collectionGo to p105/NFKB1/KBF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Plasmid Grade Plasmid quantity
pGMAP000579 0 Adenovirus plasmid Research Grade 10mg, 50mg, 100mg, 500mg, >1g
GMP-like Grade 10mg, 50mg, 100mg, 500mg, >1g
High Quality (HQ) Grade
Seed 5ug


Product Description

Catalog ID pGMAP000579
Gene Name NFKB1
Accession Number BC051765
Gene ID 4790
Species Human
Product Type Adenovirus plasmid (overexpression)
Insert Length 3896 bp
Gene Alias KBF1, EBP-1, NF-kB, CVID12, NF-kB1, NFKB-p50, NFkappaB, NF-kappaB, NFKB-p105, NF-kappa-B1, NF-kappabeta
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T40192-Ab Anti-p105 monoclonal antibody
    Target Antigen GM-Tg-g-T40192-Ag p105/NFKB1 protein
    ORF Viral Vector pGMLV002079 Human NFKB1 Lentivirus plasmid
    ORF Viral Vector pGMPC000683 Human NFKB1 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector pGMAP000579 0 Adenovirus plasmid
    ORF Viral Vector vGMLV002079 Human NFKB1 Lentivirus particle


    Target information

    Target ID GM-T40192
    Target Name p105
    Gene ID 4790, 18033, 710324, 81736, 100142683, 442859, 616115, 100067894
    Gene Symbol and Synonyms CVID12,EBP-1,KBF1,NF-kappa-B1,NF-kappaB,NF-kappaB1,NF-kappabeta,NF-kB,NF-kB1,NFkappaB,NFKB-p105,NFKB-p50,NFKB1,p105,p50,p50/p105
    Uniprot Accession P19838
    Uniprot Entry Name NFKB1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease Cancer
    Gene Ensembl ENSG00000109320
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. NFKB is a critical regulator of the immediate-early response to viral infection. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. [provided by RefSeq, Aug 2020]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.