Human SLC6A19/B0AT1/HND ORF/cDNA clone-Lentivirus plasmid (NM_001003841.3)

Cat. No.: pGMLV000887
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days

Pre-made Human SLC6A19/B0AT1/HND Lentiviral expression plasmid for SLC6A19 lentivirus packaging, SLC6A19 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.

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Product Description

Catalog ID pGMLV000887
Gene Name SLC6A19
Accession Number NM_001003841.3
Gene ID 340024
Species Human
Product Type Lentivirus plasmid (overexpression)
Insert Length 1905 bp
Gene Alias B0AT1,HND
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGTGAGGCTCGTGCTGCCCAACCCCGGCCTAGACGCCCGGATCCCGTCCCTGGCTGAGCTGGAGACCATCGAGCAGGAGGAGGCCAGCTCCCGGCCGAAGTGGGACAACAAGGCGCAGTACATGCTCACCTGCCTGGGCTTCTGCGTGGGCCTCGGCAACGTGTGGCGCTTCCCCTACCTGTGTCAGAGCCACGGAGGAGGAGCCTTCATGATCCCGTTCCTCATCCTGCTGGTCCTGGAGGGCATCCCCCTGCTGTACCTGGAGTTCGCCATCGGGCAGCGGCTGCGGCGGGGCAGCCTGGGTGTGTGGAGCTCCATCCACCCGGCCCTGAAGGGCCTAGGCCTGGCCTCCATGCTCACGTCCTTCATGGTGGGACTGTATTACAACACCATCATCTCCTGGATCATGTGGTACTTATTCAACTCCTTCCAGGAGCCTCTGCCCTGGAGCGACTGCCCGCTCAACGAGAACCAGACAGGGTATGTGGACGAGTGCGCCAGGAGCTCCCCTGTGGACTACTTCTGGTACCGAGAGACGCTCAACATCTCCACGTCCATCAGCGACTCGGGCTCCATCCAGTGGTGGATGCTGCTGTGCCTGGCCTGCGCATGGAGCGTCCTGTACATGTGCACCATCCGCGGCATCGAGACCACCGGGAAGGCCGTGTACATCACCTCCACGCTGCCCTATGTCGTCCTGACCATCTTCCTCATCCGAGGCCTGACGCTGAAGGGCGCCACCAATGGCATCGTCTTCCTCTTCACGCCCAACGTCACGGAGCTGGCCCAGCCGGACACCTGGCTGGACGCGGGCGCACAGGTCTTCTTCTCCTTCTCCCTGGCCTTCGGGGGCCTCATCTCCTTCTCCAGCTACAACTCTGTGCACAACAACTGCGAGAAGGACTCGGTGATTGTGTCCATCATCAACGGCTTCACATCGGTGTATGTGGCCATCGTGGTCTACTCCGTCATTGGGTTCCGCGCCACACAGCGCTACGACGACTGCTTCAGCACGAACATCCTGACCCTCATCAACGGGTTCGACCTGCCTGAAGGCAACGTGACCCAGGAGAACTTTGTGGACATGCAGCAGCGGTGCAACGCCTCCGACCCCGCGGCCTACGCGCAGCTGGTGTTCCAGACCTGCGACATCAACGCCTTCCTCTCAGAGGCCGTGGAGGGCACAGGCCTGGCCTTCATCGTCTTCACCGAGGCCATCACCAAGATGCCGTTGTCCCCACTGTGGTCTGTGCTCTTCTTCATTATGCTCTTCTGCCTGGGGCTGTCATCTATGTTTGGGAACATGGAGGGCGTCGTTGTGCCCCTGCAGGACCTCAGAGTCATCCCCCCGAAGTGGCCCAAGGAGGTGCTCACAGGCCTCATCTGCCTGGGGACATTCCTCATTGGCTTCATCTTCACGCTGAACTCCGGCCAGTACTGGCTCTCCCTGCTGGACAGCTATGCCGGCTCCATTCCCCTGCTCATCATCGCCTTCTGCGAGATGTTCTCTGTGGTCTACGTGTACGGTGTGGACAGGTTCAATAAGGACATCGAGTTCATGATCGGCCACAAGCCCAACATCTTCTGGCAAGTCACGTGGCGCGTGGTCAGCCCCCTGCTCATGCTGATCATCTTCCTCTTCTTCTTCGTGGTAGAGGTCAGTCAGGAGCTGACCTACAGCATCTGGGACCCTGGCTACGAGGAATTTCCCAAATCCCAGAAGATCTCCTACCCGAACTGGGTGTATGTGGTGGTGGTGATTGTGGCTGGAGTGCCCTCCCTCACCATCCCTGGCTATGCCATCTACAAGCTCATCAGGAACCACTGCCAGAAGCCAGGGGACCATCAGGGGCTGGTGAGCACACTGTCCACAGCCTCCATGAACGGGGACCTGAAGTACTGA
ORF Protein Sequence MVRLVLPNPGLDARIPSLAELETIEQEEASSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVLEGIPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFNSFQEPLPWSDCPLNENQTGYVDECARSSPVDYFWYRETLNISTSISDSGSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTLKGATNGIVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSIINGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASDPAAYAQLVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSMFGNMEGVVVPLQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMFSVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIIFLFFFVVEVSQELTYSIWDPGYEEFPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQKPGDHQGLVSTLSTASMNGDLKY

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP1657-Ab Anti-S6A19/ SLC6A19/ B0AT1 monoclonal antibody
    Target Antigen GM-Tg-g-MP1657-Ag SLC6A19 VLP (virus-like particle)
    ORF Viral Vector pGMLP001736 Human SLC6A19 Lentivirus plasmid
    ORF Viral Vector pGMLV000887 Human SLC6A19 Lentivirus plasmid
    ORF Viral Vector vGMLP001736 Human SLC6A19 Lentivirus particle
    ORF Viral Vector vGMLV000887 Human SLC6A19 Lentivirus particle


    Target information

    Target ID GM-MP1657
    Target Name SLC6A19
    Gene ID 340024, 74338, 100424683, 664630, 123380628, 100683912, 100337416, 100069470
    Gene Symbol and Synonyms 4632401C08Rik,B0AT1,B<0>AT1,HND,SLC6A19
    Uniprot Accession Q695T7
    Uniprot Entry Name S6A19_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Not Available
    Gene Ensembl ENSG00000174358
    Target Classification Not Available

    This gene encodes a system B(0) transmembrane protein that actively transports most neutral amino acids across the apical membrane of epithelial cells. Mutations in this gene may result in Hartnup disorder, an inherited disease with symptoms such as pellagra, cerebellar ataxia, and psychosis. The expression and function of B0AT1 (SLC6A19) in intestinal cells depends on the presence of the accessory protein angiotensin-converting enzyme 2 (ACE2) which, among other functions, acts as a chaperone for membrane trafficking of B0AT1. The ACE2 is also the cellular receptor for severe acute respiratory syndrome-coronavirus (SARS-CoV) and for SARS-CoV-2 that is causing the coronavirus 2019 (COVID-19) pandemic [provided by RefSeq, Jul 2020]



    About GMVC

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    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.