Human TPT1/HRF/p02 ORF/cDNA clone-Lentivirus plasmid (NM_003295.4)
Cat. No.: pGMLV001169
Size: 10 µg
Concentration: generally 0.5ug/ul, usually not less than 0.3ug/ul
Leading Time: 3-7 working days
Pre-made Human TPT1/HRF/p02 Lentiviral expression plasmid for TPT1 lentivirus packaging, TPT1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product Description
Catalog ID | pGMLV001169 |
Gene Name | TPT1 |
Accession Number | NM_003295.4 |
Gene ID | 7178 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 519 bp |
Gene Alias | HRF,p02,p23,TCTP |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGATTATCTACCGGGACCTCATCAGCCACGATGAGATGTTCTCCGACATCTACAAGATCCGGGAGATCGCGGACGGGTTGTGCCTGGAGGTGGAGGGGAAGATGGTCAGTAGGACAGAAGGTAACATTGATGACTCGCTCATTGGTGGAAATGCCTCCGCTGAAGGCCCCGAGGGCGAAGGTACCGAAAGCACAGTAATCACTGGTGTCGATATTGTCATGAACCATCACCTGCAGGAAACAAGTTTCACAAAAGAAGCCTACAAGAAGTACATCAAAGATTACATGAAATCAATCAAAGGGAAACTTGAAGAACAGAGACCAGAAAGAGTAAAACCTTTTATGACAGGGGCTGCAGAACAAATCAAGCACATCCTTGCTAATTTCAAAAACTACCAGTTCTTTATTGGTGAAAACATGAATCCAGATGGCATGGTTGCTCTATTGGACTACCGTGAGGATGGTGTGACCCCATATATGATTTTCTTTAAGGATGGTTTAGAAATGGAAAAATGTTAA |
ORF Protein Sequence | MIIYRDLISHDEMFSDIYKIREIADGLCLEVEGKMVSRTEGNIDDSLIGGNASAEGPEGEGTESTVITGVDIVMNHHLQETSFTKEAYKKYIKDYMKSIKGKLEEQRPERVKPFMTGAAEQIKHILANFKNYQFFIGENMNPDGMVALLDYREDGVTPYMIFFKDGLEMEKC |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T77473-Ab | Anti-TPT1 monoclonal antibody |
Target Antigen | GM-Tg-g-T77473-Ag | TPT1 protein |
ORF Viral Vector | pGMLP000637 | Human TPT1 Lentivirus plasmid |
ORF Viral Vector | pGMLV001169 | Human TPT1 Lentivirus plasmid |
ORF Viral Vector | vGMLP000637 | Human TPT1 Lentivirus particle |
ORF Viral Vector | vGMLV001169 | Human TPT1 Lentivirus particle |
Target information
Target ID | GM-T77473 |
Target Name | TPT1 |
Gene ID | 7178, 22070, 702155, 116646, 101083564, 476924, 326599, 100059158 |
Gene Symbol and Synonyms | HRF,p02,p21,p23,TCTP,TPT1,Trt |
Uniprot Accession | P13693 |
Uniprot Entry Name | TCTP_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Cancer |
Gene Ensembl | ENSG00000133112 |
Target Classification | Tumor-associated antigen (TAA) |
This gene encodes a protein that is a regulator of cellular growth and proliferation. Its mRNA is highly structured and contains an oligopyrimidine tract (5'-TOP) in its 5' untranslated region that functions to repress its translation under quiescent conditions. The encoded protein is involved in a variety of cellular pathways, including apoptosis, protein synthesis and cell division. It binds to and stabilizes microtubules, and removal of this protein through phosphorylation is required for progression through mitotic and meiotic cell divisions. This gene is known to play a role in carcinogenesis, and is upregulated in some cancer cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
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