Human SMAD1/BSP-1/ BSP1 ORF/cDNA clone-Lentivirus particle (NM_001003688)

Pre-made Human SMAD1/BSP-1/ BSP1 Lentiviral expression plasmid for SMAD1 lentivirus packaging, SMAD1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Target products collectionGo to SMAD1/BSP-1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP000523 Human SMAD1 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP000523
Gene Name SMAD1
Accession Number NM_001003688
Gene ID 4086
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 1398 bp
Gene Alias BSP-1, BSP1, JV4-1, JV41, MADH1, MADR1
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
Sequence ATGAATGTGACAAGTTTATTTTCCTTTACAAGTCCAGCTGTGAAGAGACTTCTTGGGTGGAAACAGGGCGATGAAGAAGAAAAATGGGCAGAGAAAGCTGTTGATGCTTTGGTGAAAAAACTGAAGAAAAAGAAAGGTGCCATGGAGGAACTGGAAAAGGCCTTGAGCTGCCCAGGGCAACCGAGTAACTGTGTCACCATTCCCCGCTCTCTGGATGGCAGGCTGCAAGTCTCCCACCGGAAGGGACTGCCTCATGTCATTTACTGCCGTGTGTGGCGCTGGCCCGATCTTCAGAGCCACCATGAACTAAAACCACTGGAATGCTGTGAGTTTCCTTTTGGTTCCAAGCAGAAGGAGGTCTGCATCAATCCCTACCACTATAAGAGAGTAGAAAGCCCTGTACTTCCTCCTGTGCTGGTTCCAAGACACAGCGAATATAATCCTCAGCACAGCCTCTTAGCTCAGTTCCGTAACTTAGGACAAAATGAGCCTCACATGCCACTCAACGCCACTTTTCCAGATTCTTTCCAGCAACCCAACAGCCACCCGTTTCCTCACTCTCCCAATAGCAGTTACCCAAACTCTCCTGGGAGCAGCAGCAGCACCTACCCTCACTCTCCCACCAGCTCAGACCCAGGAAGCCCTTTCCAGATGCCAGCTGATACGCCCCCACCTGCTTACCTGCCTCCTGAAGACCCCATGACCCAGGATGGCTCTCAGCCGATGGACACAAACATGATGGCGCCTCCCCTGCCCTCAGAAATCAACAGAGGAGATGTTCAGGCGGTTGCTTATGAGGAACCAAAACACTGGTGCTCTATTGTCTACTATGAGCTCAACAATCGTGTGGGTGAAGCGTTCCATGCCTCCTCCACAAGTGTGTTGGTGGATGGTTTCACTGATCCTTCCAACAATAAGAACCGTTTCTGCCTTGGGCTGCTCTCCAATGTTAACCGGAATTCCACTATTGAAAACACCAGGCGGCATATTGGAAAAGGAGTTCATCTTTATTATGTTGGAGGGGAGGTGTATGCCGAATGCCTTAGTGACAGTAGCATCTTTGTGCAAAGTCGGAACTGCAACTACCATCATGGATTTCATCCTACTACTGTTTGCAAGATCCCTAGTGGGTGTAGTCTGAAAATTTTTAACAACCAAGAATTTGCTCAGTTATTGGCACAGTCTGTGAACCATGGATTTGAGACAGTCTATGAGCTTACAAAAATGTGTACTATACGTATGAGCTTTGTGAAGGGCTGGGGAGCAGAATACCACCGCCAGGATGTTACTAGCACCCCCTGCTGGATTGAGATACATCTGCACGGCCCCCTCCAGTGGCTGGATAAAGTTCTTACTCAAATGGGTTCACCTCATAATCCTATTTCATCTGTATCTTAA

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP2743-Ab Anti-SMAD1 monoclonal antibody
    Target Antigen GM-Tg-g-IP2743-Ag SMAD1 protein
    Cytokine cks-Tg-g-GM-IP2743 SMAD family member 1 (SMAD1) protein & antibody
    ORF Viral Vector pGMLP000523 Human SMAD1 Lentivirus plasmid
    ORF Viral Vector pGMAP000218 Human SMAD1 Adenovirus plasmid
    ORF Viral Vector pGMLP-SPh-043 Human SMAD1 Lentivirus plasmid
    ORF Viral Vector pGMAP-SPh-183 Human SMAD1 Adenovirus plasmid
    ORF Viral Vector vGMLP000523 Human SMAD1 Lentivirus particle
    ORF Viral Vector vGMAP000218 Human SMAD1 Adenovirus particle
    ORF Viral Vector vGMLP-SPh-043 Human SMAD1 Lentivirus particle
    ORF Viral Vector vGMAP-SPh-183 Human SMAD1 Adenovirus particle
    ORF Viral Vector pGMLV002299 Human SMAD1 Lentivirus plasmid


    Target information

    Target ID GM-IP2743
    Target Name SMAD1
    Gene ID 4086, 17125, 574340, 25671, 101085713, 475456, 540488, 100033850
    Gene Symbol and Synonyms BSP-1,BSP1,dwf-A,JV4-1,JV41,Mad1,MADH1,MADR1,Mlp1,mMad1,MusMLP,SMAD1
    Uniprot Accession Q15797
    Uniprot Entry Name SMAD1_HUMAN
    Protein Sub-location Introcelluar Protein
    Category Cytokine Target
    Disease Cancer
    Gene Ensembl ENSG00000170365
    Target Classification Tumor-associated antigen (TAA)

    The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]



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