Human IL13/IL-13/P600 ORF/cDNA clone-Lentivirus particle (NM_002188)

Cat. No.: vGMLP000547

Pre-made Human IL13/IL-13/P600 Lentiviral expression plasmid for IL13 lentivirus packaging, IL13 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP000547 Human IL13 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP000547
Gene Name IL13
Accession Number NM_002188
Gene ID 3596
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 441 bp
Gene Alias IL-13,P600
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCATCCGCTCCTCAATCCTCTCCTGTTGGCACTGGGCCTCATGGCGCTTTTGTTGACCACGGTCATTGCTCTCACTTGCCTTGGCGGCTTTGCCTCCCCAGGCCCTGTGCCTCCCTCTACAGCCCTCAGGGAGCTCATTGAGGAGCTGGTCAACATCACCCAGAACCAGAAGGCTCCGCTCTGCAATGGCAGCATGGTATGGAGCATCAACCTGACAGCTGGCATGTACTGTGCAGCCCTGGAATCCCTGATCAACGTGTCAGGCTGCAGTGCCATCGAGAAGACCCAGAGGATGCTGAGCGGATTCTGCCCGCACAAGGTCTCAGCTGGGCAGTTTTCCAGCTTGCATGTCCGAGACACCAAAATCGAGGTGGCCCAGTTTGTAAAGGACCTGCTCTTACATTTAAAGAAACTTTTTCGCGAGGGACAGTTCAACTGA
ORF Protein Sequence MHPLLNPLLLALGLMALLLTTVIALTCLGGFASPGPVPPSTALRELIEELVNITQNQKAPLCNGSMVWSINLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGQFN

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-098 Pre-Made Cendakimab biosimilar, Whole mAb, Anti-IL13 Antibody: Anti-IL-13/P600 therapeutic antibody
    Biosimilar GMP-Bios-ab-136 Pre-Made Dectrekumab biosimilar, Whole mAb, Anti-IL13 Antibody: Anti-IL-13/P600 therapeutic antibody
    Biosimilar GMP-Bios-ab-004 Pre-Made Abrezekimab biosimilar, Fab, Anti-IL13 Antibody: Anti-IL-13/P600 therapeutic antibody
    Biosimilar GMP-Bios-ab-592 Pre-Made Tralokinumab biosimilar, Whole mAb, Anti-IL13 Antibody: Anti-IL-13/P600 therapeutic antibody
    Biosimilar GMP-Bios-ab-199 Pre-Made Etokimab biosimilar, Whole mAb, Anti-IL13 Antibody: Anti-IL-13/P600 therapeutic antibody
    Biosimilar GMP-Bios-ab-492 Pre-Made Romilkimab biosimilar, Bispecific Dual Variable Domain IG, Anti-IL13;IL4 Antibody: Anti-IL-13/P600;BCGF-1/BCGF1/BSF-1/BSF1/IL-4 therapeutic antibody
    Biosimilar GMP-Bios-ab-027 Pre-Made Anrukinzumab biosimilar, Whole mAb, Anti-IL13 Antibody: Anti-IL-13/P600 therapeutic antibody
    Biosimilar GMP-Bios-ab-299 Pre-Made Lebrikizumab biosimilar, Whole mAb, Anti-IL13 Antibody: Anti-IL-13/P600 therapeutic antibody
    Target Antibody GM-Tg-g-T29143-Ab Anti-IL13/ IL-13/ P600 functional antibody
    Target Antigen GM-Tg-g-T29143-Ag IL13 protein
    ORF Viral Vector pGMLP000547 Human IL13 Lentivirus plasmid
    ORF Viral Vector pGMAP000460 Human IL13 Adenovirus plasmid
    ORF Viral Vector pGMLP-IL-017 Human IL13 Lentivirus plasmid
    ORF Viral Vector pGMAP-IL-100 Human IL13 Adenovirus plasmid
    ORF Viral Vector vGMLP000547 Human IL13 Lentivirus particle
    ORF Viral Vector vGMAP000460 Human IL13 Adenovirus particle
    ORF Viral Vector vGMLP-IL-017 Human IL13 Lentivirus particle
    ORF Viral Vector vGMAP-IL-100 Human IL13 Adenovirus particle


    Target information

    Target ID GM-T29143
    Target Name IL13
    Gene ID 3596, 16163, 574325, 116553, 101084678, 442990, 281247, 100034113
    Gene Symbol and Synonyms IL-13,IL13,P600
    Uniprot Accession P35225
    Uniprot Entry Name IL13_HUMAN
    Protein Sub-location Secreted Protein/Potential Cytokines
    Category Therapeutics Target, Immuno-oncology Target, INN Index
    Disease Breast Cancer, asthma, Malignant neoplasm of bladder
    Gene Ensembl ENSG00000169194
    Target Classification Checkpoint-Immuno Oncology

    This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]



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