Human TIGIT/VSIG9/VSTM3 ORF/cDNA clone-Lentivirus particle (NM_173799)

Cat. No.: vGMLP004203

Pre-made Human TIGIT/VSIG9/VSTM3 Lentiviral expression plasmid for TIGIT lentivirus packaging, TIGIT lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP004203 Human TIGIT Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP004203
Gene Name TIGIT
Accession Number NM_173799
Gene ID 201633
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 735 bp
Gene Alias VSIG9,VSTM3,WUCAM
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGCGCTGGTGTCTCCTCCTGATCTGGGCCCAGGGGCTGAGGCAGGCTCCCCTCGCCTCAGGAATGATGACAGGCACAATAGAAACAACGGGGAACATTTCTGCAGAGAAAGGTGGCTCTATCATCTTACAATGTCACCTCTCCTCCACCACGGCACAAGTGACCCAGGTCAACTGGGAGCAGCAGGACCAGCTTCTGGCCATTTGTAATGCTGACTTGGGGTGGCACATCTCCCCATCCTTCAAGGATCGAGTGGCCCCAGGTCCCGGCCTGGGCCTCACCCTCCAGTCGCTGACCGTGAACGATACAGGGGAGTACTTCTGCATCTATCACACCTACCCTGATGGGACGTACACTGGGAGAATCTTCCTGGAGGTCCTAGAAAGCTCAGTGGCTGAGCACGGTGCCAGGTTCCAGATTCCATTGCTTGGAGCCATGGCCGCGACGCTGGTGGTCATCTGCACAGCAGTCATCGTGGTGGTCGCGTTGACTAGAAAGAAGAAAGCCCTCAGAATCCATTCTGTGGAAGGTGACCTCAGGAGAAAATCAGCTGGACAGGAGGAATGGAGCCCCAGTGCTCCCTCACCCCCAGGAAGCTGTGTCCAGGCAGAAGCTGCACCTGCTGGGCTCTGTGGAGAGCAGCGGGGAGAGGACTGTGCCGAGCTGCATGACTACTTCAATGTCCTGAGTTACAGAAGCCTGGGTAACTGCAGCTTCTTCACAGAGACTGGTTAG
ORF Protein Sequence MRWCLLLIWAQGLRQAPLASGMMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIPLLGAMAATLVVICTAVIVVVALTRKKKALRIHSVEGDLRRKSAGQEEWSPSAPSPPGSCVQAEAAPAGLCGEQRGEDCAELHDYFNVLSYRSLGNCSFFTETG

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Biosimilar GMP-Bios-ab-699 Pre-Made Tamgiblimab biosimilar, Whole mAb, Anti-TIGIT Antibody: Anti-VSIG9/VSTM3/WUCAM therapeutic antibody
    Biosimilar GMP-Bios-ab-620 Pre-Made Vibostolimab biosimilar, Whole mAb, Anti-TIGIT Antibody: Anti-VSIG9/VSTM3/WUCAM therapeutic antibody
    Biosimilar GMP-Bios-ab-198 Pre-Made Etigilimab biosimilar, Whole mAb, Anti-TIGIT Antibody: Anti-VSIG9/VSTM3/WUCAM therapeutic antibody
    Biosimilar GMP-Bios-ab-388 Pre-Made Ociperlimab biosimilar, Whole mAb, Anti-TIGIT Antibody: Anti-VSIG9/VSTM3/WUCAM therapeutic antibody
    Biosimilar GMP-Bios-ab-579 Pre-Made Tiragolumab biosimilar, Whole mAb, Anti-TIGIT Antibody: Anti-VSIG9/VSTM3/WUCAM therapeutic antibody
    Biosimilar GMP-Bios-ab-152 Pre-Made Domvanalimab biosimilar, Whole mAb, Anti-TIGIT Antibody: Anti-VSIG9/VSTM3/WUCAM therapeutic antibody
    Target Antibody GM-Tg-g-T40874-Ab Anti-TIGIT/ VSIG9/ VSTM3 monoclonal antibody
    Target Antigen GM-Tg-g-T40874-Ag TIGIT VLP (virus-like particle)
    ORF Viral Vector pGMLP004203 Human TIGIT Lentivirus plasmid
    ORF Viral Vector pGMLV001721 Human TIGIT Lentivirus plasmid
    ORF Viral Vector pGMPC004773 Human TIGIT Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP004203 Human TIGIT Lentivirus particle
    ORF Viral Vector vGMLV001721 Human TIGIT Lentivirus particle


    Target information

    Target ID GM-T40874
    Target Name TIGIT
    Gene ID 201633, 100043314, 710941, 363784, 101098326, 487986, 100140801, 100071301
    Gene Symbol and Synonyms RGD1563191,TIGIT,VSIG9,VSTM3,WUCAM
    Uniprot Accession Q495A1
    Uniprot Entry Name TIGIT_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target, Immuno-oncology Target, INN Index
    Disease Not Available
    Gene Ensembl ENSG00000181847
    Target Classification Checkpoint-Immuno Oncology

    This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]



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