Human RAB7A/PRO2706/RAB7 ORF/cDNA clone-Lentivirus particle (NM_004637)
Cat. No.: vGMLP004585
Pre-made Human RAB7A/PRO2706/RAB7 Lentiviral expression plasmid for RAB7A lentivirus packaging, RAB7A lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Catalog No. | Product Name | lentivirus Grade | lentivirus quantity |
---|---|---|---|
vGMLP004585 | Human RAB7A Lentivirus particle | Pilot Grade | 1.0E+8TU |
5.0E+8TU | |||
1.0E+9TU | |||
Research Grade | 1.0E+8TU | ||
5.0E+8TU | |||
1.0E+9TU | |||
GMP-like Grade | inquiry | ||
GMP Grade | inquiry |
Product Description
Catalog ID | vGMLP004585 |
Gene Name | RAB7A |
Accession Number | NM_004637 |
Gene ID | 7879 |
Species | Human |
Product Type | Lentivirus particle (overexpression) |
Insert Length | 624 bp |
Gene Alias | PRO2706,RAB7 |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
ORF Nucleotide Sequence | ATGACCTCTAGGAAGAAAGTGTTGCTGAAGGTTATCATCCTGGGAGATTCTGGAGTCGGGAAGACATCACTCATGAACCAGTATGTGAATAAGAAATTCAGCAATCAGTACAAAGCCACAATAGGAGCTGACTTTCTGACCAAGGAGGTGATGGTGGATGACAGGCTAGTCACAATGCAGATATGGGACACAGCAGGACAGGAACGGTTCCAGTCTCTCGGTGTGGCCTTCTACAGAGGTGCAGACTGCTGCGTTCTGGTATTTGATGTGACTGCCCCCAACACATTCAAAACCCTAGATAGCTGGAGAGATGAGTTTCTCATCCAGGCCAGTCCCCGAGATCCTGAAAACTTCCCATTTGTTGTGTTGGGAAACAAGATTGACCTCGAAAACAGACAAGTGGCCACAAAGCGGGCACAGGCCTGGTGCTACAGCAAAAACAACATTCCCTACTTTGAGACCAGTGCCAAGGAGGCCATCAACGTGGAGCAGGCGTTCCAGACGATTGCACGGAATGCACTTAAGCAGGAAACGGAGGTGGAGCTGTACAACGAATTTCCTGAACCTATCAAACTGGACAAGAATGACCGGGCCAAGGCCTCGGCAGAAAGCTGCAGTTGCTGA |
ORF Protein Sequence | MTSRKKVLLKVIILGDSGVGKTSLMNQYVNKKFSNQYKATIGADFLTKEVMVDDRLVTMQIWDTAGQERFQSLGVAFYRGADCCVLVFDVTAPNTFKTLDSWRDEFLIQASPRDPENFPFVVLGNKIDLENRQVATKRAQAWCYSKNNIPYFETSAKEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKNDRAKASAESCSC |
Reference
Data / case study
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Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T14030-Ab | Anti-RAB7A monoclonal antibody |
Target Antigen | GM-Tg-g-T14030-Ag | RAB7A protein |
ORF Viral Vector | pGMLP004585 | Human RAB7A Lentivirus plasmid |
ORF Viral Vector | pGMLV001325 | Human RAB7A Lentivirus plasmid |
ORF Viral Vector | pGMLV002468 | Human RAB7A Lentivirus plasmid |
ORF Viral Vector | pGMPC000402 | Human RAB7A Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | pGMPC000494 | Human RAB7A Mammalian (Non-Viral Vector) plasmid |
ORF Viral Vector | vGMLP004585 | Human RAB7A Lentivirus particle |
ORF Viral Vector | vGMLV001325 | Human RAB7A Lentivirus particle |
ORF Viral Vector | vGMLV002468 | Human RAB7A Lentivirus particle |
Target information
Target ID | GM-T14030 |
Target Name | RAB7A |
Gene ID | 7879, 19349, 707280, 29448, 101085959, 404007, 509970, 100050015 |
Gene Symbol and Synonyms | CMT2B,PRO2706,RAB7,RAB7A |
Uniprot Accession | P51149 |
Uniprot Entry Name | RAB7A_HUMAN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Not Available |
Gene Ensembl | ENSG00000075785 |
Target Classification | Not Available |
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]
About GMVC
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