- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-SURF1 monoclonal antibody
Pre-made anti-SURF1 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research
Go to SURF1/SURF1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-IP1858-Ab-1/ GM-Tg-hg-IP1858-Ab-2 | Anti-Human SURF1 monoclonal antibody | Human |
| GM-Tg-rg-IP1858-Ab-1/ GM-Tg-rg-IP1858-Ab-2 | Anti-Rat SURF1 monoclonal antibody | Rat |
| GM-Tg-mg-IP1858-Ab-1/ GM-Tg-mg-IP1858-Ab-2 | Anti-Mouse SURF1 monoclonal antibody | Mouse |
| GM-Tg-cynog-IP1858-Ab-1/ GM-Tg-cynog-IP1858-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SURF1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-IP1858-Ab-1/ GM-Tg-felg-IP1858-Ab-2 | Anti-Feline SURF1 monoclonal antibody | Feline |
| GM-Tg-cang-IP1858-Ab-1/ GM-Tg-cang-IP1858-Ab-2 | Anti-Canine SURF1 monoclonal antibody | Canine |
| GM-Tg-bovg-IP1858-Ab-1/ GM-Tg-bovg-IP1858-Ab-2 | Anti-Bovine SURF1 monoclonal antibody | Bovine |
| GM-Tg-equg-IP1858-Ab-1/ GM-Tg-equg-IP1858-Ab-2 | Anti-Equine SURF1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-IP1858-Ab-1/ GM-Tg-hg-IP1858-Ab-2; GM-Tg-rg-IP1858-Ab-1/ GM-Tg-rg-IP1858-Ab-2; GM-Tg-mg-IP1858-Ab-1/ GM-Tg-mg-IP1858-Ab-2; GM-Tg-cynog-IP1858-Ab-1/ GM-Tg-cynog-IP1858-Ab-2; GM-Tg-felg-IP1858-Ab-1/ GM-Tg-felg-IP1858-Ab-2; GM-Tg-cang-IP1858-Ab-1/ GM-Tg-cang-IP1858-Ab-2; GM-Tg-bovg-IP1858-Ab-1/ GM-Tg-bovg-IP1858-Ab-2; GM-Tg-equg-IP1858-Ab-1/ GM-Tg-equg-IP1858-Ab-2 |
| Products Name | Anti-SURF1 monoclonal antibody |
| Format | mab |
| Target Name | SURF1 |
| Protein Sub-location | Introcelluar Protein |
| Category of antibody | |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected. |
| Tag | Fc |
| Products description | Pre-made anti-SURF1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-IP1858-Ag-1 | Recombinant multi-species SURF1/ CMT4K protein |
| ORF Viral Vector | pGMLP003881 | human SURF1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002818 | human SURF1 Lentivirus particle |
| ORF Viral Vector | pGMLP002818 | human SURF1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003881 | human SURF1 Lentivirus particle |
| ORF Viral Vector | pGMLPm002280 | mouse Surf1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002280 | mouse Surf1 Lentivirus particle |
Target information
| Target ID | GM-IP1858 |
| Target Name | SURF1 |
| Gene ID | 6834,20930,64463,722212,480681,101085249,100139115 |
| Gene Symbol and Synonyms | 0610010F23Rik,Ab1-205,CMT4K,MC4DN1,SHY1,Surf-1,SURF1 |
| Uniprot Accession | Q15526,Q9QXU2 |
| Uniprot Entry Name | SURF1_HUMAN,SURF1_RAT |
| Protein Sub-location | Introcelluar Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000148290 |
| Target Classification | N/A |
The target: SURF1, gene name: SURF1, also named as CMT4K. This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
