Anti-PSMD9 monoclonal antibody

Pre-made anti-PSMD9 monoclonal antibody(mab)-benchmark antibody for ELISA, affinity binding assay, drug discovery and mechanism of action (MOA) research

Target products collectionGo to PSMD9/PSMD9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-IP2677-Ab-1/ GM-Tg-hg-IP2677-Ab-2Anti-Human PSMD9 monoclonal antibodyHuman
GM-Tg-rg-IP2677-Ab-1/ GM-Tg-rg-IP2677-Ab-2Anti-Rat PSMD9 monoclonal antibodyRat
GM-Tg-mg-IP2677-Ab-1/ GM-Tg-mg-IP2677-Ab-2Anti-Mouse PSMD9 monoclonal antibodyMouse
GM-Tg-cynog-IP2677-Ab-1/ GM-Tg-cynog-IP2677-Ab-2Anti-Cynomolgus/ Rhesus macaque PSMD9 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-IP2677-Ab-1/ GM-Tg-felg-IP2677-Ab-2Anti-Feline PSMD9 monoclonal antibodyFeline
GM-Tg-cang-IP2677-Ab-1/ GM-Tg-cang-IP2677-Ab-2Anti-Canine PSMD9 monoclonal antibodyCanine
GM-Tg-bovg-IP2677-Ab-1/ GM-Tg-bovg-IP2677-Ab-2Anti-Bovine PSMD9 monoclonal antibodyBovine
GM-Tg-equg-IP2677-Ab-1/ GM-Tg-equg-IP2677-Ab-2Anti-Equine PSMD9 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-IP2677-Ab-1/ GM-Tg-hg-IP2677-Ab-2; GM-Tg-rg-IP2677-Ab-1/ GM-Tg-rg-IP2677-Ab-2;
GM-Tg-mg-IP2677-Ab-1/ GM-Tg-mg-IP2677-Ab-2; GM-Tg-cynog-IP2677-Ab-1/ GM-Tg-cynog-IP2677-Ab-2;
GM-Tg-felg-IP2677-Ab-1/ GM-Tg-felg-IP2677-Ab-2; GM-Tg-cang-IP2677-Ab-1/ GM-Tg-cang-IP2677-Ab-2;
GM-Tg-bovg-IP2677-Ab-1/ GM-Tg-bovg-IP2677-Ab-2; GM-Tg-equg-IP2677-Ab-1/ GM-Tg-equg-IP2677-Ab-2
Products NameAnti-PSMD9 monoclonal antibody
Formatmab
Target NamePSMD9
Protein Sub-locationIntrocelluar Protein
Category of antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by ELISA with recombinant soluble protein antigen. The potency in neutralizing, inhibiting or blocking of the target protein is not detected.
TagFc
Products descriptionPre-made anti-PSMD9 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenGM-Tg-g-IP2677-Ag-1Recombinant multi-species PSMD9/ Rpn4/ p27 protein
    ORF Viral VectorvGMLP002650human PSMD9 Lentivirus particle
    ORF Viral VectorpGMAP000241Human PSMD9 Adenovirus plasmid
    ORF Viral VectorvGMAP000241Human PSMD9 Adenovirus particle
    ORF Viral VectorpGMLP002650human PSMD9 Lentivirus plasmid
    ORF Viral VectorpGMLPm002427mouse Psmd9 Lentivirus plasmid
    ORF Viral VectorvGMLPm002427mouse Psmd9 Lentivirus particle


    Target information

    Target IDGM-IP2677
    Target NamePSMD9
    Gene ID5715,67151,161475,701174,477467,101093051,513315,100058668
    Gene Symbol and Synonyms1500011J20Rik,2610202L11Rik,Bridge,Bridge-1,p27,PSMD9,Rpn4
    Uniprot AccessionO00233,Q9WTV5,Q3SZ19
    Uniprot Entry NamePSMD9_HUMAN,PSMD9_RAT,PSMD9_BOVIN
    Protein Sub-locationIntrocelluar Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000110801
    Target ClassificationN/A

    The target: PSMD9, gene name: PSMD9, also named as Rpn4, p27. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, May 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.