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Anti-DEGS1/ DEGS/ DEGS-1 monoclonal antibody
Anti-DEGS1/ DEGS/ DEGS-1 antibody for FACS & in-vivo assay
Go to DEGS1/DEGS1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP0355-Ab-1/ GM-Tg-hg-MP0355-Ab-2 | Anti-Human DEGS1 monoclonal antibody | Human |
| GM-Tg-rg-MP0355-Ab-1/ GM-Tg-rg-MP0355-Ab-2 | Anti-Rat DEGS1 monoclonal antibody | Rat |
| GM-Tg-mg-MP0355-Ab-1/ GM-Tg-mg-MP0355-Ab-2 | Anti-Mouse DEGS1 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP0355-Ab-1/ GM-Tg-cynog-MP0355-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DEGS1 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP0355-Ab-1/ GM-Tg-felg-MP0355-Ab-2 | Anti-Feline DEGS1 monoclonal antibody | Feline |
| GM-Tg-cang-MP0355-Ab-1/ GM-Tg-cang-MP0355-Ab-2 | Anti-Canine DEGS1 monoclonal antibody | Canine |
| GM-Tg-bovg-MP0355-Ab-1/ GM-Tg-bovg-MP0355-Ab-2 | Anti-Bovine DEGS1 monoclonal antibody | Bovine |
| GM-Tg-equg-MP0355-Ab-1/ GM-Tg-equg-MP0355-Ab-2 | Anti-Equine DEGS1 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP0355-Ab-1/ GM-Tg-hg-MP0355-Ab-2; GM-Tg-rg-MP0355-Ab-1/ GM-Tg-rg-MP0355-Ab-2; GM-Tg-mg-MP0355-Ab-1/ GM-Tg-mg-MP0355-Ab-2; GM-Tg-cynog-MP0355-Ab-1/ GM-Tg-cynog-MP0355-Ab-2; GM-Tg-felg-MP0355-Ab-1/ GM-Tg-felg-MP0355-Ab-2; GM-Tg-cang-MP0355-Ab-1/ GM-Tg-cang-MP0355-Ab-2; GM-Tg-bovg-MP0355-Ab-1/ GM-Tg-bovg-MP0355-Ab-2; GM-Tg-equg-MP0355-Ab-1/ GM-Tg-equg-MP0355-Ab-2 |
| Products Name | Anti-DEGS1 monoclonal antibody |
| Format | mab |
| Target Name | DEGS1 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DEGS1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species DEGS1/ DEGS/ DEGS-1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP002078 | human DEGS1 Lentivirus plasmid |
| ORF Viral Vector | vGMLP002078 | human DEGS1 Lentivirus particle |
| ORF Viral Vector | pGMLPm000952 | mouse Degs1 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000952 | mouse Degs1 Lentivirus particle |
Target information
| Target ID | GM-MP0355 |
| Target Name | DEGS1 |
| Gene ID | 8560,13244,702128,490395,101083993,507290,100055442 |
| Gene Symbol and Synonyms | DEGS,DEGS-1,DEGS1,Des-1,DES1,FADS7,HLD18,Mdes,MIG15,MLD |
| Uniprot Accession | O15121,Q3ZBY7 |
| Uniprot Entry Name | DEGS1_HUMAN,DEGS1_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000143753 |
| Target Classification | N/A |
The target: DEGS1, gene name: DEGS1, also named as DEGS, DEGS-1, DES1, Des-1, FADS7, MIG15, MLD. This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. [provided by RefSeq, Mar 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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