Anti-EVA1A/ FAM176A/ ™EM166 monoclonal antibody

Anti-EVA1A/ FAM176A/ ™EM166 antibody for FACS & in-vivo assay

Target products collectionGo to EVA1A/EVA1A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP0428-Ab-1/ GM-Tg-hg-MP0428-Ab-2Anti-Human EVA1A monoclonal antibodyHuman
GM-Tg-rg-MP0428-Ab-1/ GM-Tg-rg-MP0428-Ab-2Anti-Rat EVA1A monoclonal antibodyRat
GM-Tg-mg-MP0428-Ab-1/ GM-Tg-mg-MP0428-Ab-2Anti-Mouse EVA1A monoclonal antibodyMouse
GM-Tg-cynog-MP0428-Ab-1/ GM-Tg-cynog-MP0428-Ab-2Anti-Cynomolgus/ Rhesus macaque EVA1A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP0428-Ab-1/ GM-Tg-felg-MP0428-Ab-2Anti-Feline EVA1A monoclonal antibodyFeline
GM-Tg-cang-MP0428-Ab-1/ GM-Tg-cang-MP0428-Ab-2Anti-Canine EVA1A monoclonal antibodyCanine
GM-Tg-bovg-MP0428-Ab-1/ GM-Tg-bovg-MP0428-Ab-2Anti-Bovine EVA1A monoclonal antibodyBovine
GM-Tg-equg-MP0428-Ab-1/ GM-Tg-equg-MP0428-Ab-2Anti-Equine EVA1A monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP0428-Ab-1/ GM-Tg-hg-MP0428-Ab-2; GM-Tg-rg-MP0428-Ab-1/ GM-Tg-rg-MP0428-Ab-2;
GM-Tg-mg-MP0428-Ab-1/ GM-Tg-mg-MP0428-Ab-2; GM-Tg-cynog-MP0428-Ab-1/ GM-Tg-cynog-MP0428-Ab-2;
GM-Tg-felg-MP0428-Ab-1/ GM-Tg-felg-MP0428-Ab-2; GM-Tg-cang-MP0428-Ab-1/ GM-Tg-cang-MP0428-Ab-2;
GM-Tg-bovg-MP0428-Ab-1/ GM-Tg-bovg-MP0428-Ab-2; GM-Tg-equg-MP0428-Ab-1/ GM-Tg-equg-MP0428-Ab-2
Products NameAnti-EVA1A monoclonal antibody
Formatmab
Target NameEVA1A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-EVA1A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species EVA1A/ FAM176A/ ™EM166 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMAD000066human EVA1A Adenovirus particle
    ORF Viral VectorvGMLV000817human EVA1A Lentivirus particle
    ORF Viral VectorpGMLV000817human EVA1A Lentivirus plasmid
    ORF Viral VectorpGMAD000066human EVA1A Adenovirus plasmid
    ORF Viral VectorpGMLPm000922mouse Eva1a Lentivirus plasmid
    ORF Viral VectorvGMLPm000922mouse Eva1a Lentivirus particle


    Target information

    Target IDGM-MP0428
    Target NameEVA1A
    Gene ID84141,232146,500221,710843,483095,101080449,528994,100068811
    Gene Symbol and SynonymsEVA1A,FAM176A,RGD1559797,™EM166
    Uniprot AccessionQ9H8M9
    Uniprot Entry NameEVA1A_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000115363
    Target ClassificationN/A

    The target: EVA1A, gene name: EVA1A, also named as FAM176A, ™EM166. Predicted to be involved in apoptotic process and autophagy. Located in intracellular membrane-bounded organelle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.