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Anti-SCN3B/ ATFB16/ BRGDA7 monoclonal antibody
Anti-SCN3B/ ATFB16/ BRGDA7 antibody for FACS & in-vivo assay
Go to SCN3B/SCN3B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1489-Ab-1/ GM-Tg-hg-MP1489-Ab-2 | Anti-Human SCN3B monoclonal antibody | Human |
| GM-Tg-rg-MP1489-Ab-1/ GM-Tg-rg-MP1489-Ab-2 | Anti-Rat SCN3B monoclonal antibody | Rat |
| GM-Tg-mg-MP1489-Ab-1/ GM-Tg-mg-MP1489-Ab-2 | Anti-Mouse SCN3B monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1489-Ab-1/ GM-Tg-cynog-MP1489-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SCN3B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1489-Ab-1/ GM-Tg-felg-MP1489-Ab-2 | Anti-Feline SCN3B monoclonal antibody | Feline |
| GM-Tg-cang-MP1489-Ab-1/ GM-Tg-cang-MP1489-Ab-2 | Anti-Canine SCN3B monoclonal antibody | Canine |
| GM-Tg-bovg-MP1489-Ab-1/ GM-Tg-bovg-MP1489-Ab-2 | Anti-Bovine SCN3B monoclonal antibody | Bovine |
| GM-Tg-equg-MP1489-Ab-1/ GM-Tg-equg-MP1489-Ab-2 | Anti-Equine SCN3B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1489-Ab-1/ GM-Tg-hg-MP1489-Ab-2; GM-Tg-rg-MP1489-Ab-1/ GM-Tg-rg-MP1489-Ab-2; GM-Tg-mg-MP1489-Ab-1/ GM-Tg-mg-MP1489-Ab-2; GM-Tg-cynog-MP1489-Ab-1/ GM-Tg-cynog-MP1489-Ab-2; GM-Tg-felg-MP1489-Ab-1/ GM-Tg-felg-MP1489-Ab-2; GM-Tg-cang-MP1489-Ab-1/ GM-Tg-cang-MP1489-Ab-2; GM-Tg-bovg-MP1489-Ab-1/ GM-Tg-bovg-MP1489-Ab-2; GM-Tg-equg-MP1489-Ab-1/ GM-Tg-equg-MP1489-Ab-2 |
| Products Name | Anti-SCN3B monoclonal antibody |
| Format | mab |
| Target Name | SCN3B |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SCN3B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SCN3B/ ATFB16/ BRGDA7 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP005128 | human SCN3B Lentivirus plasmid |
| ORF Viral Vector | vGMLP005128 | human SCN3B Lentivirus particle |
| ORF Viral Vector | pGMLPm002416 | mouse Scn3b Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002416 | mouse Scn3b Lentivirus particle |
Target information
| Target ID | GM-MP1489 |
| Target Name | SCN3B |
| Gene ID | 55800,235281,245956,714673,610239,101088103,540925,100071718 |
| Gene Symbol and Synonyms | 1110001K16Rik,4833414B02Rik,ATFB16,BRGDA7,HSA243396,SCN3B,SCNB3 |
| Uniprot Accession | Q9NY72,Q9JK00,Q2KI11 |
| Uniprot Entry Name | SCN3B_HUMAN,SCN3B_RAT,SCN3B_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000166257 |
| Target Classification | N/A |
The target: SCN3B, gene name: SCN3B, also named as ATFB16, BRGDA7, HSA243396, SCNB3. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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