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Anti-STX3/ STX3A monoclonal antibody
Anti-STX3/ STX3A antibody for FACS & in-vivo assay
Go to STX3/STX3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1727-Ab-1/ GM-Tg-hg-MP1727-Ab-2 | Anti-Human STX3 monoclonal antibody | Human |
| GM-Tg-rg-MP1727-Ab-1/ GM-Tg-rg-MP1727-Ab-2 | Anti-Rat STX3 monoclonal antibody | Rat |
| GM-Tg-mg-MP1727-Ab-1/ GM-Tg-mg-MP1727-Ab-2 | Anti-Mouse STX3 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1727-Ab-1/ GM-Tg-cynog-MP1727-Ab-2 | Anti-Cynomolgus/ Rhesus macaque STX3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1727-Ab-1/ GM-Tg-felg-MP1727-Ab-2 | Anti-Feline STX3 monoclonal antibody | Feline |
| GM-Tg-cang-MP1727-Ab-1/ GM-Tg-cang-MP1727-Ab-2 | Anti-Canine STX3 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1727-Ab-1/ GM-Tg-bovg-MP1727-Ab-2 | Anti-Bovine STX3 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1727-Ab-1/ GM-Tg-equg-MP1727-Ab-2 | Anti-Equine STX3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1727-Ab-1/ GM-Tg-hg-MP1727-Ab-2; GM-Tg-rg-MP1727-Ab-1/ GM-Tg-rg-MP1727-Ab-2; GM-Tg-mg-MP1727-Ab-1/ GM-Tg-mg-MP1727-Ab-2; GM-Tg-cynog-MP1727-Ab-1/ GM-Tg-cynog-MP1727-Ab-2; GM-Tg-felg-MP1727-Ab-1/ GM-Tg-felg-MP1727-Ab-2; GM-Tg-cang-MP1727-Ab-1/ GM-Tg-cang-MP1727-Ab-2; GM-Tg-bovg-MP1727-Ab-1/ GM-Tg-bovg-MP1727-Ab-2; GM-Tg-equg-MP1727-Ab-1/ GM-Tg-equg-MP1727-Ab-2 |
| Products Name | Anti-STX3 monoclonal antibody |
| Format | mab |
| Target Name | STX3 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-STX3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species STX3/ STX3A VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP000571 | human STX3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP000571 | human STX3 Lentivirus particle |
| ORF Viral Vector | pGMLPm000452 | mouse Stx3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000452 | mouse Stx3 Lentivirus particle |
Target information
| Target ID | GM-MP1727 |
| Target Name | STX3 |
| Gene ID | 6809,20908,81802,698953,100855648,101099148,513275,100060878 |
| Gene Symbol and Synonyms | DIAR12,MVID2,RDMVID,STX3,STX3A,Syn-3 |
| Uniprot Accession | Q13277,Q08849 |
| Uniprot Entry Name | STX3_HUMAN,STX3_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000166900 |
| Target Classification | N/A |
The target: STX3, gene name: STX3, also named as STX3A. The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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