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Anti-™127/ ™EM127 monoclonal antibody
Anti-™127/ ™EM127 antibody for FACS & in-vivo assay
Go to ™EM127/™EM127 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1818-Ab-1/ GM-Tg-hg-MP1818-Ab-2 | Anti-Human ™EM127 monoclonal antibody | Human |
| GM-Tg-rg-MP1818-Ab-1/ GM-Tg-rg-MP1818-Ab-2 | Anti-Rat ™EM127 monoclonal antibody | Rat |
| GM-Tg-mg-MP1818-Ab-1/ GM-Tg-mg-MP1818-Ab-2 | Anti-Mouse ™EM127 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1818-Ab-1/ GM-Tg-cynog-MP1818-Ab-2 | Anti-Cynomolgus/ Rhesus macaque ™EM127 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1818-Ab-1/ GM-Tg-felg-MP1818-Ab-2 | Anti-Feline ™EM127 monoclonal antibody | Feline |
| GM-Tg-cang-MP1818-Ab-1/ GM-Tg-cang-MP1818-Ab-2 | Anti-Canine ™EM127 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1818-Ab-1/ GM-Tg-bovg-MP1818-Ab-2 | Anti-Bovine ™EM127 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1818-Ab-1/ GM-Tg-equg-MP1818-Ab-2 | Anti-Equine ™EM127 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1818-Ab-1/ GM-Tg-hg-MP1818-Ab-2; GM-Tg-rg-MP1818-Ab-1/ GM-Tg-rg-MP1818-Ab-2; GM-Tg-mg-MP1818-Ab-1/ GM-Tg-mg-MP1818-Ab-2; GM-Tg-cynog-MP1818-Ab-1/ GM-Tg-cynog-MP1818-Ab-2; GM-Tg-felg-MP1818-Ab-1/ GM-Tg-felg-MP1818-Ab-2; GM-Tg-cang-MP1818-Ab-1/ GM-Tg-cang-MP1818-Ab-2; GM-Tg-bovg-MP1818-Ab-1/ GM-Tg-bovg-MP1818-Ab-2; GM-Tg-equg-MP1818-Ab-1/ GM-Tg-equg-MP1818-Ab-2 |
| Products Name | Anti-™EM127 monoclonal antibody |
| Format | mab |
| Target Name | ™EM127 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-™EM127 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ™127/ ™EM127 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP000811 | human ™EM127 Lentivirus particle |
| ORF Viral Vector | pGMLP000811 | human ™EM127 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm002253 | mouse Tmem127 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002253 | mouse Tmem127 Lentivirus particle |
Target information
| Target ID | GM-MP1818 |
| Target Name | ™EM127 |
| Gene ID | 55654,69470,311405,705069,609057,101091188,513620,100062454 |
| Gene Symbol and Synonyms | 2310003P10Rik,RGD1309744,™EM127 |
| Uniprot Accession | O75204 |
| Uniprot Entry Name | ™127_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000135956 |
| Target Classification | N/A |
The target: ™EM127, gene name: ™EM127, also named as . This gene encodes a transmembrane protein with 3 predicted transmembrane domains. The protein is associated with a subpopulation of vesicular organelles corresponding to early endosomal structures, with the Golgi, and with lysosomes, and may participate in protein trafficking between these structures. Mutations in this gene and several other genes cause pheochromocytomas. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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