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Anti-UPK3B/ P35/ UP3B monoclonal antibody
Anti-UPK3B/ P35/ UP3B antibody for FACS & in-vivo assay
Go to UPK3B/UPK3B products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1909-Ab-1/ GM-Tg-hg-MP1909-Ab-2 | Anti-Human UPK3B monoclonal antibody | Human |
| GM-Tg-rg-MP1909-Ab-1/ GM-Tg-rg-MP1909-Ab-2 | Anti-Rat UPK3B monoclonal antibody | Rat |
| GM-Tg-mg-MP1909-Ab-1/ GM-Tg-mg-MP1909-Ab-2 | Anti-Mouse UPK3B monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1909-Ab-1/ GM-Tg-cynog-MP1909-Ab-2 | Anti-Cynomolgus/ Rhesus macaque UPK3B monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1909-Ab-1/ GM-Tg-felg-MP1909-Ab-2 | Anti-Feline UPK3B monoclonal antibody | Feline |
| GM-Tg-cang-MP1909-Ab-1/ GM-Tg-cang-MP1909-Ab-2 | Anti-Canine UPK3B monoclonal antibody | Canine |
| GM-Tg-bovg-MP1909-Ab-1/ GM-Tg-bovg-MP1909-Ab-2 | Anti-Bovine UPK3B monoclonal antibody | Bovine |
| GM-Tg-equg-MP1909-Ab-1/ GM-Tg-equg-MP1909-Ab-2 | Anti-Equine UPK3B monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1909-Ab-1/ GM-Tg-hg-MP1909-Ab-2; GM-Tg-rg-MP1909-Ab-1/ GM-Tg-rg-MP1909-Ab-2; GM-Tg-mg-MP1909-Ab-1/ GM-Tg-mg-MP1909-Ab-2; GM-Tg-cynog-MP1909-Ab-1/ GM-Tg-cynog-MP1909-Ab-2; GM-Tg-felg-MP1909-Ab-1/ GM-Tg-felg-MP1909-Ab-2; GM-Tg-cang-MP1909-Ab-1/ GM-Tg-cang-MP1909-Ab-2; GM-Tg-bovg-MP1909-Ab-1/ GM-Tg-bovg-MP1909-Ab-2; GM-Tg-equg-MP1909-Ab-1/ GM-Tg-equg-MP1909-Ab-2 |
| Products Name | Anti-UPK3B monoclonal antibody |
| Format | mab |
| Target Name | UPK3B |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-UPK3B benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species UPK3B/ P35/ UP3B VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP005058 | human UPK3B Lentivirus particle |
| ORF Viral Vector | pGMLP005058 | human UPK3B Lentivirus plasmid |
| ORF Viral Vector | pGMLPm003509 | mouse Upk3b Lentivirus plasmid |
| ORF Viral Vector | vGMLPm003509 | mouse Upk3b Lentivirus particle |
Target information
| Target ID | GM-MP1909 |
| Target Name | UPK3B |
| Gene ID | 105375355,100647,360790,715377,607577,101083641,282115,100060861 |
| Gene Symbol and Synonyms | P35,PMS2L14,RGD1309615,UP3B,UPIIIB,UPK3B |
| Uniprot Accession | Q9BT76,Q864V4 |
| Uniprot Entry Name | UPK3B_HUMAN,UPK3B_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000243566 |
| Target Classification | N/A |
The target: UPK3B, gene name: UPK3B, also named as P35, UP3B, UPIIIB. UPK3B is a minor component of the apical plaques of mammalian urothelium that binds and dimerizes with uroplakin-1b (UPK1B; MIM 602380), one of the major conserved urothelium membrane proteins. The other major conserved integral membrane proteins of urothelial plaques are UPK1A (MIM 611557), UPK2 (MIM 611558), and UPK3A (MIM 611559) (Deng et al., 2002 [PubMed 12446744]).[supplied by OMIM, Mar 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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