Anti-BORG5/ CDC42EP1/ CEP1 monoclonal antibody

Anti-BORG5/ CDC42EP1/ CEP1 antibody for FACS & in-vivo assay

Target products collectionGo to CDC42EP1/CDC42EP1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2043-Ab-1/ GM-Tg-hg-MP2043-Ab-2Anti-Human CDC42EP1 monoclonal antibodyHuman
GM-Tg-rg-MP2043-Ab-1/ GM-Tg-rg-MP2043-Ab-2Anti-Rat CDC42EP1 monoclonal antibodyRat
GM-Tg-mg-MP2043-Ab-1/ GM-Tg-mg-MP2043-Ab-2Anti-Mouse CDC42EP1 monoclonal antibodyMouse
GM-Tg-cynog-MP2043-Ab-1/ GM-Tg-cynog-MP2043-Ab-2Anti-Cynomolgus/ Rhesus macaque CDC42EP1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2043-Ab-1/ GM-Tg-felg-MP2043-Ab-2Anti-Feline CDC42EP1 monoclonal antibodyFeline
GM-Tg-cang-MP2043-Ab-1/ GM-Tg-cang-MP2043-Ab-2Anti-Canine CDC42EP1 monoclonal antibodyCanine
GM-Tg-bovg-MP2043-Ab-1/ GM-Tg-bovg-MP2043-Ab-2Anti-Bovine CDC42EP1 monoclonal antibodyBovine
GM-Tg-equg-MP2043-Ab-1/ GM-Tg-equg-MP2043-Ab-2Anti-Equine CDC42EP1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2043-Ab-1/ GM-Tg-hg-MP2043-Ab-2; GM-Tg-rg-MP2043-Ab-1/ GM-Tg-rg-MP2043-Ab-2;
GM-Tg-mg-MP2043-Ab-1/ GM-Tg-mg-MP2043-Ab-2; GM-Tg-cynog-MP2043-Ab-1/ GM-Tg-cynog-MP2043-Ab-2;
GM-Tg-felg-MP2043-Ab-1/ GM-Tg-felg-MP2043-Ab-2; GM-Tg-cang-MP2043-Ab-1/ GM-Tg-cang-MP2043-Ab-2;
GM-Tg-bovg-MP2043-Ab-1/ GM-Tg-bovg-MP2043-Ab-2; GM-Tg-equg-MP2043-Ab-1/ GM-Tg-equg-MP2043-Ab-2
Products NameAnti-CDC42EP1 monoclonal antibody
Formatmab
Target NameCDC42EP1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CDC42EP1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species BORG5/ CDC42EP1/ CEP1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMAP000532Human CDC42EP1 Adenovirus plasmid
    ORF Viral VectorvGMAP000532Human CDC42EP1 Adenovirus particle


    Target information

    Target IDGM-MP2043
    Target NameCDC42EP1
    Gene ID11135,104445,315121,697553,481267,101097658,511099,100054751
    Gene Symbol and Synonyms1810058K22Rik,BORG5,CDC42EP1,CEP1,MSE55
    Uniprot AccessionQ00587,A1A5P0,Q17QW1
    Uniprot Entry NameBORG5_HUMAN,BORG5_RAT,BORG5_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000128283
    Target ClassificationN/A

    The target: CDC42EP1, gene name: CDC42EP1, also named as BORG5, CEP1, MSE55. CDC42 is a member of the Rho GTPase family that regulates multiple cellular activities, including actin polymerization. The protein encoded by this gene is a CDC42 binding protein that mediates actin cytoskeleton reorganization at the plasma membrane. This protein is secreted and is primarily found in bone marrow. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.