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Anti-PAR6A/ PARD6A/ PAR-6A monoclonal antibody
Anti-PAR6A/ PARD6A/ PAR-6A antibody for FACS & in-vivo assay
Go to PARD6A/PARD6A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP2234-Ab-1/ GM-Tg-hg-MP2234-Ab-2 | Anti-Human PARD6A monoclonal antibody | Human |
| GM-Tg-rg-MP2234-Ab-1/ GM-Tg-rg-MP2234-Ab-2 | Anti-Rat PARD6A monoclonal antibody | Rat |
| GM-Tg-mg-MP2234-Ab-1/ GM-Tg-mg-MP2234-Ab-2 | Anti-Mouse PARD6A monoclonal antibody | Mouse |
| GM-Tg-cynog-MP2234-Ab-1/ GM-Tg-cynog-MP2234-Ab-2 | Anti-Cynomolgus/ Rhesus macaque PARD6A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP2234-Ab-1/ GM-Tg-felg-MP2234-Ab-2 | Anti-Feline PARD6A monoclonal antibody | Feline |
| GM-Tg-cang-MP2234-Ab-1/ GM-Tg-cang-MP2234-Ab-2 | Anti-Canine PARD6A monoclonal antibody | Canine |
| GM-Tg-bovg-MP2234-Ab-1/ GM-Tg-bovg-MP2234-Ab-2 | Anti-Bovine PARD6A monoclonal antibody | Bovine |
| GM-Tg-equg-MP2234-Ab-1/ GM-Tg-equg-MP2234-Ab-2 | Anti-Equine PARD6A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP2234-Ab-1/ GM-Tg-hg-MP2234-Ab-2; GM-Tg-rg-MP2234-Ab-1/ GM-Tg-rg-MP2234-Ab-2; GM-Tg-mg-MP2234-Ab-1/ GM-Tg-mg-MP2234-Ab-2; GM-Tg-cynog-MP2234-Ab-1/ GM-Tg-cynog-MP2234-Ab-2; GM-Tg-felg-MP2234-Ab-1/ GM-Tg-felg-MP2234-Ab-2; GM-Tg-cang-MP2234-Ab-1/ GM-Tg-cang-MP2234-Ab-2; GM-Tg-bovg-MP2234-Ab-1/ GM-Tg-bovg-MP2234-Ab-2; GM-Tg-equg-MP2234-Ab-1/ GM-Tg-equg-MP2234-Ab-2 |
| Products Name | Anti-PARD6A monoclonal antibody |
| Format | mab |
| Target Name | PARD6A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-PARD6A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species PAR6A/ PARD6A/ PAR-6A VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP001412 | human PARD6A Lentivirus plasmid |
| ORF Viral Vector | vGMLP001412 | human PARD6A Lentivirus particle |
| ORF Viral Vector | pGMLPm001395 | mouse Pard6a Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001395 | mouse Pard6a Lentivirus particle |
Target information
| Target ID | GM-MP2234 |
| Target Name | PARD6A |
| Gene ID | 50855,56513,307799,699351,489756,101101605,524653,100053411 |
| Gene Symbol and Synonyms | 0710008C04Rik,2610010A15Rik,Par-6,PAR-6A,PAR6,Par6a,PAR6alpha,PAR6C,PARD6A,TAX40,TIP-40 |
| Uniprot Accession | Q9NPB6,Q6B4M5 |
| Uniprot Entry Name | PAR6A_HUMAN,PAR6A_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000102981 |
| Target Classification | N/A |
The target: PARD6A, gene name: PARD6A, also named as PAR-6A, PAR6, PAR6C, PAR6alpha, TAX40, TIP-40. This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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