Anti-SNP23/ SNAP23/ HsT17016 monoclonal antibody

Anti-SNP23/ SNAP23/ HsT17016 antibody for FACS & in-vivo assay

Target products collectionGo to SNAP23/SNAP23 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2332-Ab-1/ GM-Tg-hg-MP2332-Ab-2Anti-Human SNAP23 monoclonal antibodyHuman
GM-Tg-rg-MP2332-Ab-1/ GM-Tg-rg-MP2332-Ab-2Anti-Rat SNAP23 monoclonal antibodyRat
GM-Tg-mg-MP2332-Ab-1/ GM-Tg-mg-MP2332-Ab-2Anti-Mouse SNAP23 monoclonal antibodyMouse
GM-Tg-cynog-MP2332-Ab-1/ GM-Tg-cynog-MP2332-Ab-2Anti-Cynomolgus/ Rhesus macaque SNAP23 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2332-Ab-1/ GM-Tg-felg-MP2332-Ab-2Anti-Feline SNAP23 monoclonal antibodyFeline
GM-Tg-cang-MP2332-Ab-1/ GM-Tg-cang-MP2332-Ab-2Anti-Canine SNAP23 monoclonal antibodyCanine
GM-Tg-bovg-MP2332-Ab-1/ GM-Tg-bovg-MP2332-Ab-2Anti-Bovine SNAP23 monoclonal antibodyBovine
GM-Tg-equg-MP2332-Ab-1/ GM-Tg-equg-MP2332-Ab-2Anti-Equine SNAP23 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2332-Ab-1/ GM-Tg-hg-MP2332-Ab-2; GM-Tg-rg-MP2332-Ab-1/ GM-Tg-rg-MP2332-Ab-2;
GM-Tg-mg-MP2332-Ab-1/ GM-Tg-mg-MP2332-Ab-2; GM-Tg-cynog-MP2332-Ab-1/ GM-Tg-cynog-MP2332-Ab-2;
GM-Tg-felg-MP2332-Ab-1/ GM-Tg-felg-MP2332-Ab-2; GM-Tg-cang-MP2332-Ab-1/ GM-Tg-cang-MP2332-Ab-2;
GM-Tg-bovg-MP2332-Ab-1/ GM-Tg-bovg-MP2332-Ab-2; GM-Tg-equg-MP2332-Ab-1/ GM-Tg-equg-MP2332-Ab-2
Products NameAnti-SNAP23 monoclonal antibody
Formatmab
Target NameSNAP23
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SNAP23 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SNP23/ SNAP23/ HsT17016 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP002382human SNAP23 Lentivirus plasmid
    ORF Viral VectorvGMLP002382human SNAP23 Lentivirus particle
    ORF Viral VectorpGMLPm000970mouse Snap23 Lentivirus plasmid
    ORF Viral VectorvGMLPm000970mouse Snap23 Lentivirus particle


    Target information

    Target IDGM-MP2332
    Target NameSNAP23
    Gene ID8773,20619,64630,708225,478268,101101473,522423,100056719
    Gene Symbol and Synonyms23kDa,HsT17016,SNAP-23,SNAP23,SNAP23A,SNAP23B,Sndt,Syndet
    Uniprot AccessionO00161,O70377
    Uniprot Entry NameSNP23_HUMAN,SNP23_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000092531
    Target ClassificationN/A

    The target: SNAP23, gene name: SNAP23, also named as HsT17016, SNAP-23A, SNAP23B, SNAP23. Specificity of vesicular transport is regulated, in part, by the interaction of a vesicle-associated membrane protein termed synaptobrevin/VAMP with a target compartment membrane protein termed syntaxin. These proteins, together with SNAP25 (synaptosome-associated protein of 25 kDa), form a complex which serves as a binding site for the general membrane fusion machinery. Synaptobrevin/VAMP and syntaxin are believed to be involved in vesicular transport in most, if not all cells, while SNAP25 is present almost exclusively in the brain, suggesting that a ubiquitously expressed homolog of SNAP25 exists to facilitate transport vesicle/target membrane fusion in other tissues. The protein encoded by this gene is structurally and functionally similar to SNAP25 and binds tightly to multiple syntaxins and synaptobrevins/VAMPs. It is an essential component of the high affinity receptor for the general membrane fusion machinery and is an important regulator of transport vesicle docking and fusion. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.