Anti-CATZ/ CTSZ/ CTSX monoclonal antibody

Anti-CATZ/ CTSZ/ CTSX antibody for FACS & in-vivo assay

Target products collectionGo to CTSZ/CTSZ products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP2579-Ab-1/ GM-Tg-hg-MP2579-Ab-2Anti-Human CTSZ monoclonal antibodyHuman
GM-Tg-rg-MP2579-Ab-1/ GM-Tg-rg-MP2579-Ab-2Anti-Rat CTSZ monoclonal antibodyRat
GM-Tg-mg-MP2579-Ab-1/ GM-Tg-mg-MP2579-Ab-2Anti-Mouse CTSZ monoclonal antibodyMouse
GM-Tg-cynog-MP2579-Ab-1/ GM-Tg-cynog-MP2579-Ab-2Anti-Cynomolgus/ Rhesus macaque CTSZ monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP2579-Ab-1/ GM-Tg-felg-MP2579-Ab-2Anti-Feline CTSZ monoclonal antibodyFeline
GM-Tg-cang-MP2579-Ab-1/ GM-Tg-cang-MP2579-Ab-2Anti-Canine CTSZ monoclonal antibodyCanine
GM-Tg-bovg-MP2579-Ab-1/ GM-Tg-bovg-MP2579-Ab-2Anti-Bovine CTSZ monoclonal antibodyBovine
GM-Tg-equg-MP2579-Ab-1/ GM-Tg-equg-MP2579-Ab-2Anti-Equine CTSZ monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP2579-Ab-1/ GM-Tg-hg-MP2579-Ab-2; GM-Tg-rg-MP2579-Ab-1/ GM-Tg-rg-MP2579-Ab-2;
GM-Tg-mg-MP2579-Ab-1/ GM-Tg-mg-MP2579-Ab-2; GM-Tg-cynog-MP2579-Ab-1/ GM-Tg-cynog-MP2579-Ab-2;
GM-Tg-felg-MP2579-Ab-1/ GM-Tg-felg-MP2579-Ab-2; GM-Tg-cang-MP2579-Ab-1/ GM-Tg-cang-MP2579-Ab-2;
GM-Tg-bovg-MP2579-Ab-1/ GM-Tg-bovg-MP2579-Ab-2; GM-Tg-equg-MP2579-Ab-1/ GM-Tg-equg-MP2579-Ab-2
Products NameAnti-CTSZ monoclonal antibody
Formatmab
Target NameCTSZ
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-CTSZ benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species CATZ/ CTSZ/ CTSX VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP002070human CTSZ Lentivirus plasmid
    ORF Viral VectorvGMLP002070human CTSZ Lentivirus particle
    ORF Viral VectorpGMLPm000564mouse Ctsz Lentivirus plasmid
    ORF Viral VectorvGMLPm000564mouse Ctsz Lentivirus particle


    Target information

    Target IDGM-MP2579
    Target NameCTSZ
    Gene ID1522,64138,252929,694157,611983,101087983,404187,100056600
    Gene Symbol and SynonymsCATX,CTSX,CTSZ,D2Wsu143e
    Uniprot AccessionQ9UBR2,Q9R1T3,P05689
    Uniprot Entry NameCATZ_HUMAN,CATZ_RAT,CATZ_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000101160
    Target ClassificationN/A

    The target: CTSZ, gene name: CTSZ, also named as CTSX. The protein encoded by this gene is a lysosomal cysteine proteinase and member of the peptidase C1 family. It exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. The encoded protein has also been known as cathepsin X and cathepsin P. This gene is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. [provided by RefSeq, Oct 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.