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Anti-DERM/ DPT/ TRAMP functional antibody
Anti-DERM/ DPT/ TRAMP functional antibody for cell culture, ELISA & in-vivo assay
Go to DPT/DPT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0894-Ab-1/ GM-Tg-hg-SE0894-Ab-2 | Anti-Human DPT monoclonal antibody | Human |
| GM-Tg-rg-SE0894-Ab-1/ GM-Tg-rg-SE0894-Ab-2 | Anti-Rat DPT monoclonal antibody | Rat |
| GM-Tg-mg-SE0894-Ab-1/ GM-Tg-mg-SE0894-Ab-2 | Anti-Mouse DPT monoclonal antibody | Mouse |
| GM-Tg-cynog-SE0894-Ab-1/ GM-Tg-cynog-SE0894-Ab-2 | Anti-Cynomolgus/ Rhesus macaque DPT monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0894-Ab-1/ GM-Tg-felg-SE0894-Ab-2 | Anti-Feline DPT monoclonal antibody | Feline |
| GM-Tg-cang-SE0894-Ab-1/ GM-Tg-cang-SE0894-Ab-2 | Anti-Canine DPT monoclonal antibody | Canine |
| GM-Tg-bovg-SE0894-Ab-1/ GM-Tg-bovg-SE0894-Ab-2 | Anti-Bovine DPT monoclonal antibody | Bovine |
| GM-Tg-equg-SE0894-Ab-1/ GM-Tg-equg-SE0894-Ab-2 | Anti-Equine DPT monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-SE0894-Ab-1/ GM-Tg-hg-SE0894-Ab-2; GM-Tg-rg-SE0894-Ab-1/ GM-Tg-rg-SE0894-Ab-2; GM-Tg-mg-SE0894-Ab-1/ GM-Tg-mg-SE0894-Ab-2; GM-Tg-cynog-SE0894-Ab-1/ GM-Tg-cynog-SE0894-Ab-2; GM-Tg-felg-SE0894-Ab-1/ GM-Tg-felg-SE0894-Ab-2; GM-Tg-cang-SE0894-Ab-1/ GM-Tg-cang-SE0894-Ab-2; GM-Tg-bovg-SE0894-Ab-1/ GM-Tg-bovg-SE0894-Ab-2; GM-Tg-equg-SE0894-Ab-1/ GM-Tg-equg-SE0894-Ab-2 |
| Products Name | Anti-DPT monoclonal antibody |
| Format | mab |
| Target Name | DPT |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by ELISA with recombinant soluble protein antigen. The biofunction of antibodies are validated with in-vitro assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-DPT benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | GM-Tg-g-SE0894-Ag-1 | Recombinant multi-species DERM/ DPT/ TRAMP protein |
| ORF Viral Vector | vGMLP004017 | human DPT Lentivirus particle |
| ORF Viral Vector | pGMLP003439 | human DPT Lentivirus plasmid |
| ORF Viral Vector | vGMLP003439 | human DPT Lentivirus particle |
| ORF Viral Vector | pGMLP004017 | human DPT Lentivirus plasmid |
| ORF Viral Vector | pGMLPm000837 | mouse Dpt Lentivirus plasmid |
| ORF Viral Vector | vGMLPm000837 | mouse Dpt Lentivirus particle |
Target information
| Target ID | GM-SE0894 |
| Target Name | DPT |
| Gene ID | 1805,56429,289178,700181,490355,101101023,504963,100057735 |
| Gene Symbol and Synonyms | 1810032B19Rik,5033416F05Rik,DPT,EQ-1,Eq1,TRAMP |
| Uniprot Accession | Q07507,P19427 |
| Uniprot Entry Name | DERM_HUMAN,DERM_BOVIN |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000143196 |
| Target Classification | N/A |
The target: DPT, gene name: DPT, also named as TRAMP. Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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