- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Bovine p-tau181 antibody and antigen (recombinant protein)
Diagnostic anti-Bovine p-tau181 antibodies pairs and antigen for animal health (animal Bovines/Cattle Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
Go to Ruminants disease testing products collection >>
Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-BOV-p-tau181-Ag01 | Bovine p-tau181 | $3090.00 |
| GMP-BOV-p-tau181-Ab01 | Anti-Bovine p-tau181 mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-BOV-p-tau181-Ab02 | Anti-Bovine p-tau181 mouse monoclonal antibody (mAb) | $3090.00 |
| GMP-BOV-p-tau181-Ab03 | Anti-Bovine p-tau181 human monoclonal antibody (mAb) | $3090.00 |
| GMP-BOV-p-tau181-Ab04 | Anti-Bovine p-tau181 human monoclonal antibody (mAb) | $3090.00 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. | GMP-BOV-p-tau181-Ag01 |
| Product Name | Bovine p-tau181 |
| Target/Biomarker | Bovine p-tau181 |
| Expression platform | E.coli |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | Anti-Bovine p-tau181 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in p-tau181 level test of animal Bovines/Cattle with Alzheimer Disease(AD). |
| Tag | His | Reconized/Reactive Specics | Bovine p-tau181 |
| Product description | Recombinant Bovine p-tau181 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-BOV-p-tau181-Ab01,GMP-BOV-p-tau181-Ab02 |
| Target/Biomarker | Bovine p-tau181 |
| Product Name | Anti-Bovine p-tau181 mouse monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Recombinant Bovine p-tau181 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine p-tau181 antibodies in Bovine p-tau181 level test of animal Bovines/Cattle with Alzheimer Disease(AD). |
| Product description | Anti-Bovine p-tau181 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine p-tau181 antibodies. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. | GMP-BOV-p-tau181-Ab03,GMP-BOV-p-tau181-Ab04 |
| Target/Biomarker | Bovine p-tau181 |
| Product Name | Anti-Bovine p-tau181 human monoclonal antibody (mAb) |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Recombinant Bovine p-tau181 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine p-tau181 antibodies in Bovine p-tau181 level test of animal Bovines/Cattle with Alzheimer Disease(AD). |
| Product description | Anti-Bovine p-tau181 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays. |
| Formulation | Lyophilized from sterile PBS, PH 7.4 |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker Information
Bovine p-tau181, the phosphorylated Tau Protein 181 variant specific to cattle, is a critical entity in the intricate domain of bovine neurobiology. At its core, it is a Tau protein that has undergone precise phosphorylation at residue 181. Tau proteins, under normal circumstances, are responsible for maintaining the stability of microtubules within neuronal cells, ensuring proper intracellular transport and the structural integrity of axons.
However, when the stage is set for neurodegenerative processes, the narrative takes an unexpected twist. Phosphorylation events can trigger the misfolding and aggregation of Tau proteins, and bovine p-tau181 is no exception. It tends to aggregate and form neurofibrillary tangles within the neural tissues of afflicted cattle.
These neurofibrillary tangles, reminiscent of those observed in human neurodegenerative diseases such as Alzheimer's, serve as a pathological signature of various bovine neurodegenerative conditions. The accumulation of p-tau181 in neurofibrillary tangles contributes to progressive neuronal dysfunction, eventually manifesting as clinical signs in conditions like bovine spongiform encephalopathy (BSE) and specific encephalopathies.
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
Facebook
LinkedIn
Twitter
