Avian Metapneumovirus Subtype D antibody and antigen (recombinant protein)

Diagnostic anti-Avian Metapneumovirus Subtype D antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease Avian metapneumovirus infection) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Avian/Bird/Poultry disease testing products collection >>


Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P198-Ag01 Recombinant Avian Metapneumovirus Subtype D protein $3090.00
GMP-VT-P198-Ab01 Anti-Avian Metapneumovirus Subtype D mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P198-Ab02 Anti-Avian Metapneumovirus Subtype D mouse monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P198-Ag01
Product Name Recombinant Avian Metapneumovirus Subtype D protein
Pathogen Avian Metapneumovirus Subtype D
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Avian Metapneumovirus Subtype D antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Avian Metapneumovirus Subtype D level test of animal Avian/Bird/Poultry infectious disease with Avian metapneumovirus infection.
Tag His
Product description Recombinant Avian Metapneumovirus Subtype D proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P198-Ab01,GMP-VT-P198-Ab02
Pathogen Avian Metapneumovirus Subtype D
Product Name Anti-Avian Metapneumovirus Subtype D mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Avian Metapneumovirus Subtype D antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avian Metapneumovirus Subtype D antibodies in Avian Metapneumovirus Subtype D level test of animal Avian/Bird/Poultry infectious disease with Avian metapneumovirus infection.
Product description Anti-Avian Metapneumovirus Subtype D mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Avian Metapneumovirus Subtype D antibodies./td>
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Pathogen


    Avian Metapneumovirus Subtype D, a subtype of avian metapneumovirus, also known as turkey rhinotracheitis virus (TRTV) or avian pneumovirus type C (APV-C), is a single-stranded negative-sense RNA virus that belongs to the family Paramyxoviridae. This highly infectious virus is responsible for significant economic losses in the poultry industry, specifically affecting turkeys.

    The genome of Avian Metapneumovirus Subtype D codes for several structural proteins, including nucleoprotein (N), phosphoprotein (P), matrix protein (M), fusion protein (F), and attachment glycoprotein (G). The F protein plays a crucial role in the ability of the virus to infect cells by facilitating membrane fusion between viral and host cell membranes, while the G protein mediates viral attachment to host cells. The M protein is involved in virion assembly and release, and the N and P proteins are essential for viral RNA replication.

    The primary mode of transmission for Avian Metapneumovirus Subtype D is believed to be through direct contact or aerosols of contaminated secretions from infected birds. The virus can cause mild to severe respiratory disease in turkeys, chickens, pheasants, and guinea fowl, with turkeys being the most susceptible.

    Clinical signs of infection include coughing, sneezing, nasal discharge, and conjunctivitis, which result from inflammation and damage to the respiratory epithelium. In severe cases, infected birds may demonstrate increased mortality rates or decreased egg production.

    Early diagnosis of Avian Metapneumovirus Subtype D is critical for disease control and management. Diagnostic methods for the virus include virus isolation, antigen detection, and molecular detection using nucleic acid-based methods such as reverse transcription PCR (RT-PCR) targeting genes such as the N or F gene. ELISA assays can detect the presence of neutralizing antibodies in infected birds.

    Outbreaks of Avian Metapneumovirus Subtype D can cause significant economic losses due to the decreased egg production and increased mortality rate of infected birds, leading to reduced productivity in poultry farming practices. Effective prevention measures include good biosecurity practices, vaccination of susceptible birds with inactivated or live attenuated vaccines, and quarantine measures for newly introduced birds to prevent contact with infected animals.

    In conclusion, Avian Metapneumovirus Subtype D is a highly infectious respiratory pathogen in birds that primarily infects turkeys and can cause significant economic losses in the poultry industry. The virus is classified as a single-stranded negative-sense RNA virus and can cause mild to severe respiratory disease in turkeys, chickens, pheasants, and guinea fowl. Accurate diagnosis and early identification of infected animals are crucial for effective control and prevention of outbreaks. Effective prevention measures include good biosecurity practices, vaccination of susceptible birds, and quarantine measures for newly introduced birds.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.