Human TERT/CMM9/ DKCA2 ORF/cDNA clone-Lentivirus plasmid (NM_198253.2)
Pre-made Human TERT/CMM9/ DKCA2 Lentiviral expression plasmid for TERT lentivirus packaging, TERT lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
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Product information
Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
---|---|---|---|
pGMLV000009 | Human TERT Lentivirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
High Quality (HQ) Grade | |||
Seed | 5ug |
Product Description
Catalog ID | pGMLV000009 |
Gene Name | TERT |
Accession Number | NM_198253.2 |
Gene ID | 7015 |
Species | Human |
Product Type | Lentivirus plasmid (overexpression) |
Insert Length | 3399 bp |
Gene Alias | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT |
Fluorescent Reporter | ZsGreen |
Mammalian Cell Selection | Puromyocin |
Fusion Tag | 3xflag (C-Terminal) |
Promoter | CMV |
Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
---|---|---|
Target Antibody | GM-Tg-g-T86052-Ab | Anti-TERT/ CMM9/ DKCA2 monoclonal antibody |
Target Antigen | GM-Tg-g-T86052-Ag | TERT VLP (virus-like particle) |
ORF Viral Vector | pGMLV000009 | Human TERT Lentivirus plasmid |
ORF Viral Vector | pGMLV000364 | Human TERT Lentivirus plasmid |
ORF Viral Vector | pGMLV000557 | Human TERT Lentivirus plasmid |
ORF Viral Vector | pGMLV000884 | Human TERT Lentivirus plasmid |
ORF Viral Vector | pGMLV000895 | Human TERT Lentivirus plasmid |
ORF Viral Vector | pGMLV001191 | Human TERT Lentivirus plasmid |
ORF Viral Vector | pGMLV001299 | Human TERT Lentivirus plasmid |
ORF Viral Vector | pGMLV001811 | Human TERT Lentivirus plasmid |
ORF Viral Vector | pGMAD000360 | Rat Tert Adenovirus plasmid |
ORF Viral Vector | pGMAD000402 | Human TERT Adenovirus plasmid |
ORF Viral Vector | pGMAD000476 | Rat Tert Adenovirus plasmid |
ORF Viral Vector | pGMAD000737 | Rat Tert Adenovirus plasmid |
ORF Viral Vector | pGMAAV001044 | Rat Tert Adeno-associate virus(AAV) plasmid |
ORF Viral Vector | vGMLV000009 | Human TERT Lentivirus particle |
ORF Viral Vector | vGMLV000364 | Human TERT Lentivirus particle |
ORF Viral Vector | vGMLV000557 | Human TERT Lentivirus particle |
ORF Viral Vector | vGMLV000884 | Human TERT Lentivirus particle |
ORF Viral Vector | vGMLV000895 | Human TERT Lentivirus particle |
ORF Viral Vector | vGMLV001191 | Human TERT Lentivirus particle |
ORF Viral Vector | vGMLV001299 | Human TERT Lentivirus particle |
ORF Viral Vector | vGMLV001811 | Human TERT Lentivirus particle |
ORF Viral Vector | vGMAD000360 | Rat Tert Adenovirus particle |
ORF Viral Vector | vGMAD000402 | Human TERT Adenovirus particle |
ORF Viral Vector | vGMAD000476 | Rat Tert Adenovirus particle |
ORF Viral Vector | vGMAD000737 | Rat Tert Adenovirus particle |
ORF Viral Vector | vGMAAV001044 | Rat Tert Adeno-associate virus(AAV) particle |
Target information
Target ID | GM-T86052 |
Target Name | TERT |
Gene ID | 7015, 21752, 709865, 301965, 100144612, 403412, 518884, 100630695 |
Gene Symbol and Synonyms | CMM9,DKCA2,DKCB4,EST2,hEST2,hTRT,PFBMFT1,TCS1,TERT,TP2,TR,TRT |
Uniprot Accession | O14746 |
Uniprot Entry Name | TERT_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | Therapeutics Target, Immuno-oncology Target |
Disease | Cancer |
Gene Ensembl | ENSG00000164362 |
Target Classification | Checkpoint-Immuno Oncology, Tumor-associated antigen (TAA) |
Telomerase is a ribonucleoprotein polymerase that maintains telomere ends by addition of the telomere repeat TTAGGG. The enzyme consists of a protein component with reverse transcriptase activity, encoded by this gene, and an RNA component which serves as a template for the telomere repeat. Telomerase expression plays a role in cellular senescence, as it is normally repressed in postnatal somatic cells resulting in progressive shortening of telomeres. Deregulation of telomerase expression in somatic cells may be involved in oncogenesis. Studies in mouse suggest that telomerase also participates in chromosomal repair, since de novo synthesis of telomere repeats may occur at double-stranded breaks. Alternatively spliced variants encoding different isoforms of telomerase reverse transcriptase have been identified; the full-length sequence of some variants has not been determined. Alternative splicing at this locus is thought to be one mechanism of regulation of telomerase activity. [provided by RefSeq, Jul 2008]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.