- • Up to 20%-50%* off first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- • Animal health test
- • In-vitro diagnostics
- • Food & Feed Safety
- • Environmental Safety
- • New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Human EGFR/ERBB/ ERBB1 ORF/cDNA clone-Lentivirus plasmid (NM_005228.3)
Pre-made Human EGFR/ERBB/ ERBB1 Lentiviral expression plasmid for EGFR lentivirus packaging, EGFR lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.
Our GM-Lentiviral vector is seamlessly integrated with the GM lentivirus packaging system. Discover more about the GM lentivirus packaging system.
Go
to EGFR/ERBB products collection
>>
(antibodies,
antigen, VLP, mRNA, ORF viral vector, etc)
Product information
| Catalog No. | Product Name | Plasmid Grade | Plasmid quantity |
|---|---|---|---|
| pGMLV000217 | Human EGFR Lentivirus plasmid | Research Grade | 10mg, 50mg, 100mg, 500mg, >1g |
| GMP-like Grade | 10mg, 50mg, 100mg, 500mg, >1g | ||
| High Quality (HQ) Grade | |||
| Seed | 5ug |
Product Description
| Catalog ID | pGMLV000217 |
| Gene Name | EGFR |
| Accession Number | NM_005228.3 |
| Gene ID | 1956 |
| Species | Human |
| Product Type | Lentivirus plasmid (overexpression) |
| Insert Length | 3633 bp |
| Gene Alias | ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA |
| Fluorescent Reporter | ZsGreen |
| Mammalian Cell Selection | Puromyocinmyocin |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | CMV |
| Resistance | Amplicin |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Target information
| Target ID | GM-T59328 |
| Target Name | EGFR |
| Gene ID | 1956, 13649, 613027, 24329, 100510799, 404306, 407217, 100067755 |
| Gene Symbol and Synonyms | 9030024J15Rik,EGFR,ERBB,ErbB-1,ERBB1,Errb1,ERRP,HER1,mENA,NISBD2,PIG61,wa-2,wa2,Wa5 |
| Uniprot Accession | P00533 |
| Uniprot Entry Name | EGFR_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Immuno-oncology Target, INN Index, Cytokine Target |
| Disease | Breast Cancer, Non-Small Cell Lung Cancer, gastric cancer, apoptosis, Asphyxia neonatorum, Urinary bladder urothelial carcinoma |
| Gene Ensembl | ENSG00000146648 |
| Target Classification | Checkpoint-Immuno Oncology, Kinase |
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor, thus inducing receptor dimerization and tyrosine autophosphorylation leading to cell proliferation. Mutations in this gene are associated with lung cancer. EGFR is a component of the cytokine storm which contributes to a severe form of Coronavirus Disease 2019 (COVID-19) resulting from infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). [provided by RefSeq, Jul 2020]
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.
Facebook
LinkedIn
Twitter
