Human HTR2A/HTR2/ 5-HT2A ORF/cDNA clone-Adenovirus particle (BC069356)

Pre-made Human HTR2A/HTR2/ 5-HT2A Adenovirus for HTR2A overexpression in-vitro and in-vivo. The HTR2A adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified HTR2A-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.

At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.

Target products collectionGo to HTR2A/HTR2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)



Product information

Catalog No. Product Name Adenovirus Grade Adenovirus quantity
vGMAP000503 Human HTR2A Adenovirus particle Research Grade-In vitro 1E+10PFU (1E+10pfu/ml×1ml)
5E+10PFU (1E+10pfu/ml×5ml)
1E+11PFU (1E+10pfu/ml×10ml)
Research Grade-In vivo 1E+11PFU (1E+11pfu/ml×1ml)
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMAP000503
Gene Name HTR2A
Accession Number BC069356
Gene ID 3356
Species Human
Product Type Adenovirus particle (overexpression)
Insert Length bp
Gene Alias HTR2, 5-HT2A
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-T32060-Ab Anti-5HT2A/ HTR2A/ 5-HT2A monoclonal antibody
    Target Antigen GM-Tg-g-T32060-Ag HTR2A VLP (virus-like particle)
    ORF Viral Vector pGMLP002120 Human HTR2A Lentivirus plasmid
    ORF Viral Vector pGMAP000503
    ORF Viral Vector vGMLP002120 Human HTR2A Lentivirus particle
    ORF Viral Vector vGMAP000503 Human HTR2A Adenovirus particle


    Target information

    Target ID GM-T32060
    Target Name HTR2A
    Gene ID 3356, 15558, 613032, 29595, 101081108, 403882, 407230, 100009685
    Gene Symbol and Synonyms 5-HT-2,5-HT-2A,5-HT2A,5-HTR2A,5Ht-2,5HT2A,5HTR2A,E030013E04,Htr-2,HTR2,HTR2A
    Uniprot Accession P28223
    Uniprot Entry Name 5HT2A_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Therapeutics Target
    Disease Schizophrenia
    Gene Ensembl ENSG00000102468
    Target Classification GPCR

    This gene encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in this gene are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of this gene show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]



    About GMVC

    GDU



    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.