Human CLDN7/claudin-1/Hs.84359 ORF/cDNA clone-Lentivirus particle (BC001055)

Cat. No.: vGMLP000382

Pre-made Human CLDN7/claudin-1/Hs.84359 Lentiviral expression plasmid for CLDN7 lentivirus packaging, CLDN7 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP000382 Human CLDN7 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP000382
Gene Name CLDN7
Accession Number BC001055
Gene ID 1366
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 636 bp
Gene Alias claudin-1,Hs.84359
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGGCCAATTCGGGCCTGCAGTTGCTGGGCTTCTCCATGGCCCTGCTGGGCTGGGTGGGTCTGGTGGCCTGCACCGCCATCCCGCAGTGGCAGATGAGCTCCTATGCGGGTGACAACATCATCACGGCCCAGGCCATGTACAAGGGGCTGTGGATGGACTGCGTCACGCAGAGCACGGGGATGATGAGCTGCAAAATGTACGACTCGGTGCTCGCCCTGTCCGCGGCCTTGCAGGCCACTCGAGCCCTAATGGTGGTCTCCCTGGTGCTGGGCTTCCTGGCCATGTTTGTGGCCACGATGGGCATGAAGTGCACGCGCTGTGGGGGAGACGACAAAGTGAAGAAGGCCCGTATAGCCATGGGTGGAGGCATAATTTTCATCGTGGCAGGTCTTGCCACCTTGGTAGCTTGCTCCTGGTATGGCCATCAGATTGTCACAGACTTTTATAACCCTTTGATCCCTACCAACATTAAGTATGAGTTTGGCCCTGCCATCTTTATTGGCTGGGCAGGGTCTGCCCTAGTCATCCTGGGAGGTGCACTGCTCTCCTGTTCCTGTCCTGGGAATGAGAGCAAGGCTGGGTACCGTGCACCCCGCTCTTACCCTAAGTCCAACTCTTCCAAGGAGTATGTGTGA
ORF Protein Sequence MANSGLQLLGFSMALLGWVGLVACTAIPQWQMSSYAGDNIITAQAMYKGLWMDCVTQSTGMMSCKMYDSVLALSAALQATRALMVVSLVLGFLAMFVATMGMKCTRCGGDDKVKKARIAMGGGIIFIVAGLATLVACSWYGHQIVTDFYNPLIPTNIKYEFGPAIFIGWAGSALVILGGALLSCSCPGNESKAGYRAPRSYPKSNSSKEYV

Reference




    Data / case study


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    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-MP0286-Ab Anti-CLD7/ CLDN7/ CEPTRL2 monoclonal antibody
    Target Antigen GM-Tg-g-MP0286-Ag CLDN7 VLP (virus-like particle)
    ORF Viral Vector pGMLP000382 Human CLDN7 Lentivirus plasmid
    ORF Viral Vector pGMAP000040 Human CLDN7 Adenovirus plasmid
    ORF Viral Vector pGMAP000104 Human CLDN7 Adenovirus plasmid
    ORF Viral Vector pGMPC000063 Human CLDN7 Mammalian (Non-Viral Vector) plasmid
    ORF Viral Vector vGMLP000382 Human CLDN7 Lentivirus particle
    ORF Viral Vector vGMAP000040 Human CLDN7 Adenovirus particle
    ORF Viral Vector vGMAP000104 Human CLDN7 Adenovirus particle


    Target information

    Target ID GM-MP0286
    Target Name CLDN7
    Gene ID 1366, 53624, 714647, 65132, 101096019, 489466, 512975, 100072960
    Gene Symbol and Synonyms CEPTRL2,claudin-1,cld-7,CLDN-7,CLDN7,CPETRL2,Hs.84359
    Uniprot Accession O95471
    Uniprot Entry Name CLD7_HUMAN
    Protein Sub-location Transmembrane Protein
    Category Not Available
    Disease Cancer
    Gene Ensembl ENSG00000181885
    Target Classification Tumor-associated antigen (TAA)

    This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.[provided by RefSeq, May 2010]



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