Adeno Associated Virus (AAV) Expression Vector (AAV expression plasmids)
Adeno Associated Virus (AAV) Expression Vector (AAV expression plasmids) - Introduction
GeneMedi's AAV expression vector also named AAV expression plasmid, is part of AAV packaging system.
GeneMedi's AAV expression vectors have been inserted with differernt expression cassettes, containing kinds of verified protomters and reporters including GFP,zsgreen, RFP, mcherry and luciferase. The GeneMedi's AAV expression vectors have been proved very suitalble for unique gene overexpression or shRNA-mediated knock-down (also called RNAi (RNA interference ). You can also achieve gene knock-out(KO) or gene editing using our Crispr-cas9-gRNA AAV expression vector.
You can produce AAV paticle in 293T cell line in high titer using GeneMedi's AAV expression vector (overexpression, shRNA or Crispr-cas9-gRNA) with GeneMedi's serotypes-specific AAV Rep-Cap plasmids and AAV helper plasmid.
GeneMedi's AAV Rep-Cap plasmids is including AAV2, AAV5, AAV6, AAV8, AAV9, AAV-PHP.B, AAV-PHP.eB, AAV PHP.s, AAV-retro (retrograde), AAV-Anc80 (L65), AAV-DJ, AAV-DJ8.
GeneMedi also supplies capsid optimized AAV variant including AAV2 variant (Y444F), AAV2 variant (Y272F, Y444F, Y500F, Y730F), AAV2 variant (Y444F, Y730F, Y500F, Y272F, Y704F, Y252F), AAV2.7m8, AAV8-1m, AAV8 variant (Y733F,Y447F) , AAV8 variant (Y733F, Y447F, Y275F) and some other engineering AAV serotypes not mentioned.